Synthesis of novel hyperbranched poly(ester-amide)s based on acidic and basic amino acids via "AD plus CBB '" couple-monomer approach

	Synthesis of novel hyperbranched poly(ester-amide)s based on acidic and basic amino acids via "AD plus CBB '" couple-monomer approach
	Bao YM ; He J ; Li YS
刊名	polymer
	2012
卷号	53 期号:1 页码:145-152
关键词	BB'(2) TYPE MONOMERS THERMAL POLYMERIZATION BIODEGRADABLE POLYMERS AROMATIC POLYAMIDES DNA DELIVERY L-ALANINE L-LYSINE AMIDE)S DEGRADATION POLYESTERS
ISSN号	0032-3861
通讯作者	li ys
中文摘要	a series of novel hydroxyl- or methyl ester- terminated hyperbranched poly(ester-amide)s (hbpeas) based on acidic (l-glumatic acid and l-aspartic acid) and basic amino acids (l-lysine) have been synthesized via the "ad + cbb'" couple-monomer approach. the abb' intermediates were stoichiometrically formed through thio-ene reaction benefited from reactivity differences between functional groups. without any purification, in situ self-polycondensations of the intermediates at elevated temperature in the presence of ti(obu)(4), as a catalyst, afforded hbpeas with high molecular weights. more rapid polymerization rate and much higher molecular weight as well as broader polydispersity were observed for the polymerization process of intermediates based on acidic amino acids than basic amino acids which is related to the catalytic mechanism and structure difference of intermediates. moreover, polymerization of intermediate derived from l-aspartic acid was carried out faster by comparison with that from l-glumatic acid. the db values were approximately estimated to be 47%-49% for the polymers derived from l-aspartic acid and l-glutamic acid. the resultant hbpeas possessed glass transition temperature (t-g) in the range of 3 to 11 degrees c, among which those derived from l-lysine shows the highest tg, and decomposition temperatures at 10% weight loss under air and nitrogen are in close regions of 261-271 degrees c and 264-268 degrees c, respectively. (c) 2011 elsevier ltd. all rights reserved.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000300073600016
公开日期	2013-06-09
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/48405]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Bao YM,He J,Li YS. Synthesis of novel hyperbranched poly(ester-amide)s based on acidic and basic amino acids via "AD plus CBB '" couple-monomer approach[J]. polymer,2012,53(1):145-152.
APA	Bao YM,He J,&Li YS.(2012).Synthesis of novel hyperbranched poly(ester-amide)s based on acidic and basic amino acids via "AD plus CBB '" couple-monomer approach.polymer,53(1),145-152.
MLA	Bao YM,et al."Synthesis of novel hyperbranched poly(ester-amide)s based on acidic and basic amino acids via "AD plus CBB '" couple-monomer approach".polymer 53.1(2012):145-152.