Facile construction of functional biosurface via SI-ATRP and "click glycosylation"

	Facile construction of functional biosurface via SI-ATRP and "click glycosylation"
	Song WT ; Xiao CS ; Cui LG ; Tang ZH ; Zhuang XL ; Chen XS
刊名	colloids and surfaces b-biointerfaces
	2012
卷号	93 页码:188-194
关键词	TRANSFER RADICAL POLYMERIZATION CARBOHYDRATE BRUSHES SURFACE CHEMISTRY IMMOBILIZATION GLYCOPOLYMERS COMBINATION ADHESION LIGANDS
ISSN号	0927-7765
通讯作者	chen xs
中文摘要	construction of high density glycosylated surfaces is important in the investigation of interactions between pathogens and surface carbohydrates. in this work, we provided a flexible method for glycosyl surface fabrication by combination of surface-initiated atom transfer radical polymerization (si-atrp) and copper-catalyzed azide-alkyne 1,3-dipolar cycloaddition (cuaac) reaction. through this strategy, we got a very high surface glycosyl density of about 4 nmol/cm(2) with the surface "click" efficiency of nearly 50%. then the carbohydrate decorated surfaces were used to mimic cell surfaces and specific recognition of mannose with escherichia coil was observed. we believe the methodology provided here can be used as a facile way for construction of a wide range of functional biosurfaces. (c) 2012 elsevier b.v. all rights reserved.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000302431900027
公开日期	2013-05-22
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/48200]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Song WT,Xiao CS,Cui LG,et al. Facile construction of functional biosurface via SI-ATRP and "click glycosylation"[J]. colloids and surfaces b-biointerfaces,2012,93:188-194.
APA	Song WT,Xiao CS,Cui LG,Tang ZH,Zhuang XL,&Chen XS.(2012).Facile construction of functional biosurface via SI-ATRP and "click glycosylation".colloids and surfaces b-biointerfaces,93,188-194.
MLA	Song WT,et al."Facile construction of functional biosurface via SI-ATRP and "click glycosylation"".colloids and surfaces b-biointerfaces 93(2012):188-194.