Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization | |
Ting Cui ; Liu XY(刘宣勇) ; Zhu YJ(朱英杰) ; Feng Chen ; Zhao Ma | |
刊名 | Journal of Colloid and Interface Science |
2011-08-12 | |
卷号 | 359页码:371-379 |
ISSN号 | 0021-9797 |
其他题名 | Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization |
通讯作者 | 朱英杰 |
中文摘要 | Amorphous calcium phosphate (ACP) has been recognized as an attractive biomaterial due to its bioactivity and biocompatibility. Electrospinning is a simple and low-cost way to fabricate polymer fibers. In this study, ACP nanoparticles with diameters ranging from 20 to 80 nm were synthesized using a simple precipitation method. ACP nanoparticles were hybridized with poly(D,L-lactic acid) (PDLLA) to form ACP/PDLLA composite nanofibers by electrospinning, and different architectures including the nanofibrous mesh and tube consisting of ACP/PDLLA composite nanofibers were obtained and characterized. The biomineralization and cytocompatibility of as-prepared ACP/PDLLA composite nanofibers were evaluated in vitro. Osteoblast-like MG63 cells were seeded on the ACP/PDLLA composite nanofiber meshes to perform the cytocompatibility evaluation. The ACP/PDLLA composite nanofibers exhibited a fast mineralization behavior in the simulated body fluid. The attachment of MG63 cells and cytotoxicity of ACP/ PDLLA composite nanofibers were also evaluated, and the experiments indicated good biocompatibility and bioactivity of ACP/PDLLA composite nanofibers. |
学科主题 | 生物材料 |
收录类别 | SCI收录 |
公开日期 | 2012-07-04 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/960] |
专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
推荐引用方式 GB/T 7714 | Ting Cui,Liu XY,Zhu YJ,et al. Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization[J]. Journal of Colloid and Interface Science,2011,359:371-379. |
APA | Ting Cui,刘宣勇,朱英杰,Feng Chen,&Zhao Ma.(2011).Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization.Journal of Colloid and Interface Science,359,371-379. |
MLA | Ting Cui,et al."Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers:Electrospinning preparation and biomineralization".Journal of Colloid and Interface Science 359(2011):371-379. |
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