The GO/rGO-Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules

	The GO/rGO-Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules
	Cheng G ; Liu YL ; Wang ZG ; Zhang JL ; Sun DH ; Ni JZ
刊名	journal of materials chemistry
	2012
卷号	22 期号:41 页码:21998-22004
关键词	GRAPHENE OXIDE CANCER BIOMARKERS SHEETS MICROSPHERES SHELL CORE
ISSN号	0959-9428
通讯作者	ni jz
中文摘要	the graphene oxide (go)-fe3o4 and the reduced graphene oxide (rgo)-fe3o4 composites with good water dispersibility, high affinity and rapid magnetic response have been prepared via a facile grafting method. they can be used for the effective immobilization of proteins and the enrichment of peptides, respectively. by taking advantage of the high loading capacity and the abundant hydrophilic groups of the go-fe3o4 composites, they can be applied to immobilize proteins. the amount of loading of protein (bsa) on go-fe3o4 is as high as 294.54 mg g(-1). the rgo-fe3o4 composites can be used to enrich the low-concentration peptides conveniently due to their high surface areas, special structures and strong magnetism. nineteen target peptides with the sequence coverage of 21% can be enriched and detected from the highly diluted digest of bsa (5 fmol mu l-1). these results reveal that the prepared go/rgo-fe3o4 composites have potential application as a carrier for biomolecule immobilization, enrichment, and separation.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000310047200030
公开日期	2013-03-18
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/47851]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Cheng G,Liu YL,Wang ZG,et al. The GO/rGO-Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules[J]. journal of materials chemistry,2012,22(41):21998-22004.
APA	Cheng G,Liu YL,Wang ZG,Zhang JL,Sun DH,&Ni JZ.(2012).The GO/rGO-Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules.journal of materials chemistry,22(41),21998-22004.
MLA	Cheng G,et al."The GO/rGO-Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules".journal of materials chemistry 22.41(2012):21998-22004.