A practical approach to stereodefined cyclopropyl-substituted heteroarenes using a Suzuki-type reaction

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	A practical approach to stereodefined cyclopropyl-substituted heteroarenes using a Suzuki-type reaction
	Yao ML(姚敏良) ; Deng MZ(邓敏智)
刊名	New J. Chem.
	2000
卷号	24 期号:6 页码:425-428
ISSN号	1144-0546
其他题名	一个用Suzuki反应来制备立体控制的环丙基取代的杂环芳烃的实用方法
通讯作者	邓敏智
英文摘要	In the presence of Pd(PPh^3)^4, NaBr and KF.2H^2O the cross-coupling reaction of heteroaryl triflates with trans-cyclopropylboronic acids proceeds readily to give pure trans-cyclopropyl heteroarenes in moderate to good yields. The X-ray crystallography of compound 3g and ~1H-NMR spectra of all products show that the configuration of the cyclopropyl group was retained during the reaction. Under the same reaction conditions. Highly optically active cyclopropyl-substituted heteroarenes(up to 94% ee) were obtained by cross-coupling of heteroary/triflates with enantiomerically enriched cyclopropylboronic acids.
学科主题	有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1039/b001051k
语种	英语
WOS记录号	WOS:000087858400012
公开日期	2013-03-07
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/23082]
专题	上海有机化学研究所_金属有机化学国家重点实验室
推荐引用方式 GB/T 7714	Yao ML,Deng MZ. A practical approach to stereodefined cyclopropyl-substituted heteroarenes using a Suzuki-type reaction[J]. New J. Chem.,2000,24(6):425-428.
APA	姚敏良,&邓敏智.(2000).A practical approach to stereodefined cyclopropyl-substituted heteroarenes using a Suzuki-type reaction.New J. Chem.,24(6),425-428.
MLA	姚敏良,et al."A practical approach to stereodefined cyclopropyl-substituted heteroarenes using a Suzuki-type reaction".New J. Chem. 24.6(2000):425-428.