1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) Catalyzed Regiospecific and Diastereoselective Reaction of Chiral N-(tert-Butanesulfinyl)ketimines and alpha,beta-Unsaturated Trifluoromethyl Ketones

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	1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) Catalyzed Regiospecific and Diastereoselective Reaction of Chiral N-(tert-Butanesulfinyl)ketimines and alpha,beta-Unsaturated Trifluoromethyl Ketones
	Zhang F(张帆) ; Liu ZJ(刘振江) ; Liu JT(刘金涛)
刊名	Chin. J. Chem.
	2011
卷号	29 期号:12 页码:2727-2731
ISSN号	1001-604X
其他题名	DBU 催化的手性N-叔丁基酮亚胺与三氟甲基α,β-不饱和酮的区域和立体选择性加成反应
通讯作者	刘金涛
英文摘要	The reaction of chiral N-(tert-butanesulfinyl)ketimines and alpha,beta-unsaturated trifluoromethyl ketones catalyzed by DBU was achieved under mild conditions. 1,2-Addition products, precursors of chiral trifluoromethylated 1,3-amino alcohols, were obtained diastereoselectively (dr value up to 95 : 5) in moderate yields (up to 76%). A possible catalytic cycle was proposed.
学科主题	氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/cjoc.201100133
语种	英语
WOS记录号	WOS:000298016700028
公开日期	2013-03-11
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/23392]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Zhang F,Liu ZJ,Liu JT. 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) Catalyzed Regiospecific and Diastereoselective Reaction of Chiral N-(tert-Butanesulfinyl)ketimines and alpha,beta-Unsaturated Trifluoromethyl Ketones[J]. Chin. J. Chem.,2011,29(12):2727-2731.
APA	张帆,刘振江,&刘金涛.(2011).1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) Catalyzed Regiospecific and Diastereoselective Reaction of Chiral N-(tert-Butanesulfinyl)ketimines and alpha,beta-Unsaturated Trifluoromethyl Ketones.Chin. J. Chem.,29(12),2727-2731.
MLA	张帆,et al."1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) Catalyzed Regiospecific and Diastereoselective Reaction of Chiral N-(tert-Butanesulfinyl)ketimines and alpha,beta-Unsaturated Trifluoromethyl Ketones".Chin. J. Chem. 29.12(2011):2727-2731.