Antibacterial diterpenoids from Sagittaria pygmaea

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	Antibacterial diterpenoids from Sagittaria pygmaea
	Liu XT(刘雪婷) ; SHI YAO ; Yu B(俞飚) ; Williams IAN D ; Sung HERMAN H Y ; ZHANG QIONG ; Liang JINGYU ; Ip NANCY Y ; MIN ZHIDA
刊名	Planta Med.
	2007
卷号	73 期号:1 页码:84-90
ISSN号	0032-0943
其他题名	从Sagittaria pygmaea中的到的有抗菌性的二萜类化合物
通讯作者	MIN ZHIDA
英文摘要	There were five new diterpenoids, 18-beta-D-3,4 -diacetoxyxylopyranosyl-ent-kaur-16-ene (1), 18-beta-L-3,5 -diacetoxyarabinofuranosyl-ent-kaur-16-ene (2), 18-beta-D-3,6 -diacetoxyglucopyranosyl-ent-kaur-16-ene (3), ent-isopimar-8(14),15-dien-19-oic acid (4), and 5 alpha-hydroxy-ent-rosa-15-en-18-oic acid (5), isolated from the whole herb of Sagittaria pygmaea. Their structures and relative configurations were established based on spectroscopic studies, chemical methods, and X-ray crystallographic analysis. Compound 2 exhibited significant antibacterial activity against the oral pathogens, Streptococcus mutans ATCC 25175 and Actinomyces viscosus ATCC 27 044, with MIC values against both pathogens of 15.6 mu g/mL. Compound 3 was active against only A. viscosus ATCC 27044 with an MIC value of 62.5 mu g/mL. Compounds 4 and 5 were active against S. mutans ATCC 25175 and A. viscosus ATCC 27044, with MIC values against both pathogens of 125.0 mu g/mL.
学科主题	生命有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1055/s-2006-951773
语种	英语
WOS记录号	WOS:000244086400014
公开日期	2013-02-25
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/19063]
专题	上海有机化学研究所_生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	Liu XT,SHI YAO,Yu B,et al. Antibacterial diterpenoids from Sagittaria pygmaea[J]. Planta Med.,2007,73(1):84-90.
APA	刘雪婷.,SHI YAO.,俞飚.,Williams IAN D.,Sung HERMAN H Y.,...&MIN ZHIDA.(2007).Antibacterial diterpenoids from Sagittaria pygmaea.Planta Med.,73(1),84-90.
MLA	刘雪婷,et al."Antibacterial diterpenoids from Sagittaria pygmaea".Planta Med. 73.1(2007):84-90.