Progress in studies of novel marine bis(indole) alkaloids

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	Progress in studies of novel marine bis(indole) alkaloids
	Yang CaiGuang ; Huang H(黄浩) ; Jiang B(姜标)
刊名	Curr. Org. Chem.
	2004
卷号	8 期号:17 页码:1691-1720
ISSN号	1385-2728
其他题名	新颖海洋双吲哚类生物碱的研究进展
通讯作者	姜标
中文摘要	The marine sponges are the source of a unique group of natural products featuring a novel skeleton, the two indole rings were directed linked by a central heterocyclic moiety. Since topsentin, a bis(indolyl)imidazole, and its analogues were isolated from Topsentia genitrix about a decade ago, scientists have isolated various novel bis(indole) alkaloids from marine organisms especially from deep-water sponges in succession. Over the last 15 years there has been an ever-increasing interest in the biological activity of these molecules. These studies became possible as a result of the scientific development of isolation, purification and total synthesis methods concomitant with the development of fairly simple in vitro tests. This paper offers a general view of the recent progress in the field of novel marine bis(indole) alkaloids, including the topsentins, nortopsentins, rhopaladins, hamacanthins, and dragmacidins family natural products. It focuses on the isolation, structure determination, and total synthesis of these bioactive alkaloids.
学科主题	天然产物有机化学
收录类别	SCI
语种	英语
WOS记录号	WOS:000224514700005
公开日期	2013-02-25
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/20205]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Yang CaiGuang,Huang H,Jiang B. Progress in studies of novel marine bis(indole) alkaloids[J]. Curr. Org. Chem.,2004,8(17):1691-1720.
APA	Yang CaiGuang,黄浩,&姜标.(2004).Progress in studies of novel marine bis(indole) alkaloids.Curr. Org. Chem.,8(17),1691-1720.
MLA	Yang CaiGuang,et al."Progress in studies of novel marine bis(indole) alkaloids".Curr. Org. Chem. 8.17(2004):1691-1720.