Free radical scavenging and antioxidant enzymes activation of polysaccharide extract from Nostoc sphaeroides

CORC > 水生生物研究所 > 中科院水生所知识产出（2009年前） > 期刊论文

	Free radical scavenging and antioxidant enzymes activation of polysaccharide extract from Nostoc sphaeroides
	Tang, Jun ; Hu, Zheng-Yu ; Chen, Xin-Wen
刊名	AMERICAN JOURNAL OF CHINESE MEDICINE
	2007
卷号	35 期号:5 页码:887-896
关键词	Nostoc sphaeroides kuetzing polysaccharide antioxidant activity scavenging effect lipid peroxidation human embryo kidney 293 cells
ISSN号	0192-415X
通讯作者	Hu, ZY, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, 7 South Donghu Rd,Wuchang Dist, Wuhan 430072, Hubei Province, Peoples R China
中文摘要	Nostoc sphaeroides Kuetzing has been used as a traditional medicine in China to treat a variety of ailments. This research identified the antioxidant activities of polysaccharide extract from Nostoc sphaeroides. The extract, which contains 46.2% carbohydrates, exhibited an effective scavenging capability on superoxide radical, hydroxyl radicals in non site-specific as well as site-specific assays, and also performed lipid peroxidation inhibition in a dose-dependent manner. Polysaccharide extract had no 1,1-diphenyl-2-picrylhydrazyl radical scavenging potential at all test concentrations. Activities of superoxide dismutase, catalase, and glutathione peroxidase in human embryo kidney 293 cells were increased effectively when Nostoc sphaeroides extract was applied. These results suggested that the use of N. sphaeroides in treating ailments may be based on the antioxidant capacities of polysaccharide composition.
英文摘要	Nostoc sphaeroides Kuetzing has been used as a traditional medicine in China to treat a variety of ailments. This research identified the antioxidant activities of polysaccharide extract from Nostoc sphaeroides. The extract, which contains 46.2% carbohydrates, exhibited an effective scavenging capability on superoxide radical, hydroxyl radicals in non site-specific as well as site-specific assays, and also performed lipid peroxidation inhibition in a dose-dependent manner. Polysaccharide extract had no 1,1-diphenyl-2-picrylhydrazyl radical scavenging potential at all test concentrations. Activities of superoxide dismutase, catalase, and glutathione peroxidase in human embryo kidney 293 cells were increased effectively when Nostoc sphaeroides extract was applied. These results suggested that the use of N. sphaeroides in treating ailments may be based on the antioxidant capacities of polysaccharide composition.
学科主题	Integrative & Complementary Medicine; Medicine ; General & Internal
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Integrative & Complementary Medicine ; Medicine, General & Internal
研究领域[WOS]	Integrative & Complementary Medicine ; General & Internal Medicine
关键词[WOS]	XIAN-MI NOSTOC ; EDIBLE CYANOBACTERIUM ; PLANT-EXTRACTS ; GROWTH ; OXYGEN
收录类别	SCI
语种	英语
WOS记录号	WOS:000250826600015
公开日期	2010-10-13
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/152342/8368]
专题	水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文
作者单位	1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei Province, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China
推荐引用方式 GB/T 7714	Tang, Jun,Hu, Zheng-Yu,Chen, Xin-Wen. Free radical scavenging and antioxidant enzymes activation of polysaccharide extract from Nostoc sphaeroides[J]. AMERICAN JOURNAL OF CHINESE MEDICINE,2007,35(5):887-896.
APA	Tang, Jun,Hu, Zheng-Yu,&Chen, Xin-Wen.(2007).Free radical scavenging and antioxidant enzymes activation of polysaccharide extract from Nostoc sphaeroides.AMERICAN JOURNAL OF CHINESE MEDICINE,35(5),887-896.
MLA	Tang, Jun,et al."Free radical scavenging and antioxidant enzymes activation of polysaccharide extract from Nostoc sphaeroides".AMERICAN JOURNAL OF CHINESE MEDICINE 35.5(2007):887-896.