Enantioselective organocatalytic Michael addition of malonates to alpha,beta-unsaturated aldehydes in water

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	Enantioselective organocatalytic Michael addition of malonates to alpha,beta-unsaturated aldehydes in water
	Ma AQ(马安琪) ; Zhu SL(朱少林) ; Ma DW(马大为)
刊名	Tetrahedron Lett.
	2008
卷号	49 期号:19 页码:3075-3077
ISSN号	0040-4039
其他题名	水相有机催化的对映选择性的丙二酸酯对α,β-不饱和醛的Michael加成反应
通讯作者	马大为
英文摘要	The Michael addition of malonates to alpha,beta-unsaturated aldehydes catalyzed by O-TMS protected diphenylprolinols and acetic acid in water occurs at 0 degrees C to rt. In most cases, the reaction runs to completion in less than 24 h. A wide range of aldehydes including beta-aryl, beta-alkyl and beta-alkenyl acroleins are found to be compatible with these conditions, providing the corresponding adducts in good yields and with good to excellent enantioselectivities. (C) 2008 Elsevier Ltd. All rights reserved.
学科主题	生命有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tetlet.2008.03.051
语种	英语
WOS记录号	WOS:000255774700011
公开日期	2013-02-19
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/15577]
专题	上海有机化学研究所_生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	Ma AQ,Zhu SL,Ma DW. Enantioselective organocatalytic Michael addition of malonates to alpha,beta-unsaturated aldehydes in water[J]. Tetrahedron Lett.,2008,49(19):3075-3077.
APA	马安琪,朱少林,&马大为.(2008).Enantioselective organocatalytic Michael addition of malonates to alpha,beta-unsaturated aldehydes in water.Tetrahedron Lett.,49(19),3075-3077.
MLA	马安琪,et al."Enantioselective organocatalytic Michael addition of malonates to alpha,beta-unsaturated aldehydes in water".Tetrahedron Lett. 49.19(2008):3075-3077.