Hydroamination of olefin in a special conjugated spiroketal enol ether system, diastereoselective synthesis of amino-containing tonghaosu analogs

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	Hydroamination of olefin in a special conjugated spiroketal enol ether system, diastereoselective synthesis of amino-containing tonghaosu analogs
	Yin BL(尹标林) ; Hu TS(胡泰山) ; Wu YL(吴毓林)
刊名	Tetrahedron Lett.
	2004
卷号	45 期号:9 页码:2017-2021
ISSN号	0040-4039
其他题名	共轭螺环烯醇醚的双键的氢胺化反应：立体选择性合成含氨基的茼蒿素类似物
通讯作者	吴毓林
英文摘要	Lithium amide reacted with spiroketal enol ether characterized tonghaosu analog at -78degreesC to give the only hydroamination product 4 in a highly regio- and diastereoselective manner. At a higher temperature, -40degreesC, the presence of free amine was critical for the hydroamination to take place; otherwise, rearrangement of tonghaosu analog to 2,3-dihydrofuran derivative like 6 was the only reaction. (C) 2004 Published by Elsevier Ltd.
学科主题	生命有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tetlet.2003.11.106
语种	英语
WOS记录号	WOS:000189116200047
公开日期	2013-01-17
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/14086]
专题	上海有机化学研究所_生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	Yin BL,Hu TS,Wu YL. Hydroamination of olefin in a special conjugated spiroketal enol ether system, diastereoselective synthesis of amino-containing tonghaosu analogs[J]. Tetrahedron Lett.,2004,45(9):2017-2021.
APA	尹标林,胡泰山,&吴毓林.(2004).Hydroamination of olefin in a special conjugated spiroketal enol ether system, diastereoselective synthesis of amino-containing tonghaosu analogs.Tetrahedron Lett.,45(9),2017-2021.
MLA	尹标林,et al."Hydroamination of olefin in a special conjugated spiroketal enol ether system, diastereoselective synthesis of amino-containing tonghaosu analogs".Tetrahedron Lett. 45.9(2004):2017-2021.