Simple synthesis of 6-(trifluoromethyl)-2,4,5,6-tetrahydropyrazolo[3,4-b]pyran derivatives by one-pot, three-component reactions

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	Simple synthesis of 6-(trifluoromethyl)-2,4,5,6-tetrahydropyrazolo[3,4-b]pyran derivatives by one-pot, three-component reactions
	Li DM(李冬梅) ; Song LP(宋力平) ; Li XF(李宪甫) ; Xing CH(邢春晖) ; Peng WM(彭卫民) ; Zhu SZ(朱仕正)
刊名	Eur. J. Org. Chem.
	2007
期号	21 页码:3520-3525
ISSN号	1434-193X
其他题名	三组分“一锅法”合成6－（三氟甲基）－2,4,5,6－四氢吡唑[3,4-b]吡喃衍生物
通讯作者	宋力平 ; 朱仕正
英文摘要	One-pot, three-component condensation reactions of aromatic aldehydes 1, 3-methylpyrazol-5-one (2) and ethyl trifluoroacetoacetate (3) provided an efficient methodology for the preparation of ethyl (4S,5R)-4-aryl-6-hydroxy-3-methyl-6-(trifluoromethyl)-2,4,5,6-tetrahyd ropyrazolo[3,4-b]- pyran-5-carboxylate derivatives (4). The reactions gave moderate to good yields under mild conditions. These new products 4 were fully characterized by spectral methods and single-crystal X-ray diffraction analysis. A plausible reaction pathway for the formation of 4 is presented. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007).
学科主题	有机氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/ejoc.200601055
语种	英语
WOS记录号	WOS:000248232100013
公开日期	2013-01-18
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/14416]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Li DM,Song LP,Li XF,et al. Simple synthesis of 6-(trifluoromethyl)-2,4,5,6-tetrahydropyrazolo[3,4-b]pyran derivatives by one-pot, three-component reactions[J]. Eur. J. Org. Chem.,2007(21):3520-3525.
APA	李冬梅,宋力平,李宪甫,邢春晖,彭卫民,&朱仕正.(2007).Simple synthesis of 6-(trifluoromethyl)-2,4,5,6-tetrahydropyrazolo[3,4-b]pyran derivatives by one-pot, three-component reactions.Eur. J. Org. Chem.(21),3520-3525.
MLA	李冬梅,et al."Simple synthesis of 6-(trifluoromethyl)-2,4,5,6-tetrahydropyrazolo[3,4-b]pyran derivatives by one-pot, three-component reactions".Eur. J. Org. Chem. .21(2007):3520-3525.