Samarium diiodide-promoted electrophilic amination of ketone enolates: efficient synthesis of quaternary carbon-containing alpha-aminated ketones

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	Samarium diiodide-promoted electrophilic amination of ketone enolates: efficient synthesis of quaternary carbon-containing alpha-aminated ketones
	Sun XW(孙兴文) ; WANG WEI ; Xu MH(徐明华) ; Lin GQ(林国强)
刊名	Tetrahedron Lett.
	2008
卷号	49 期号:40 页码:5807-5809
ISSN号	0040-4039
其他题名	Samarium diiodide-promoted electrophilic amination of ketone enolates: efficient synthesis of quaternary carbon-containing alpha-aminated ketones
通讯作者	徐明华 ; 林国强
英文摘要	An efficient and practical electrophilic amination method that allows the preparation of useful quaternary carbon-containing alpha-aminoketones was developed. The reaction proceeds regiospecifically via a samarium enolate intermediate at room temperature in the presence of mild reducing agent SmI2. Unlike the most reported lithium enolate cases, this new amination method does not require the use of strong base such as BuLi or LDA. (C) 2008 Elsevier Ltd. All rights reserved.
学科主题	有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tetlet.2008.07.123
语种	英语
WOS记录号	WOS:000259537800027
公开日期	2013-02-20
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/16665]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Sun XW,WANG WEI,Xu MH,et al. Samarium diiodide-promoted electrophilic amination of ketone enolates: efficient synthesis of quaternary carbon-containing alpha-aminated ketones[J]. Tetrahedron Lett.,2008,49(40):5807-5809.
APA	孙兴文,WANG WEI,徐明华,&林国强.(2008).Samarium diiodide-promoted electrophilic amination of ketone enolates: efficient synthesis of quaternary carbon-containing alpha-aminated ketones.Tetrahedron Lett.,49(40),5807-5809.
MLA	孙兴文,et al."Samarium diiodide-promoted electrophilic amination of ketone enolates: efficient synthesis of quaternary carbon-containing alpha-aminated ketones".Tetrahedron Lett. 49.40(2008):5807-5809.