Room-temperature highly diastereoselective Zn-mediated allylation of chiral N-tert-butanesulfinyl imines: Remarkable reaction condition controlled stereoselectivity reversal

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	Room-temperature highly diastereoselective Zn-mediated allylation of chiral N-tert-butanesulfinyl imines: Remarkable reaction condition controlled stereoselectivity reversal
	Sun XW(孙兴文) ; Xu MH(徐明华) ; Lin GQ(林国强)
刊名	Org. Lett.
	2006
卷号	8 期号:21 页码:4979-4982
ISSN号	1523-7060
其他题名	室温下金属锌参与的高非对映选择性的N-叔丁基亚磺酰胺的烯丙基化反应:优异的控制选择性翻转的反应条件
通讯作者	徐明华 ; 林国强
英文摘要	An efficient method for the highly diastereoselective synthesis of chiral homoallylic amines by Zn-mediated allylation of chiral N-tert-butanesulfinyl imines at room temperature was developed. By simply tuning the reaction conditions, the method allows the achievement of a highly remarkable opposite stereocontrol, affording the desired stereochemical outcome in good yield and with excellent diastereoselectivity (up to 98% dr). With N-sulfinyl ketimines, the corresponding quaternary carbon-containing chiral homoallylic amines could also be produced.
学科主题	有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1021/ol062216x
语种	英语
WOS记录号	WOS:000241030900078
公开日期	2013-02-20
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/16649]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Sun XW,Xu MH,Lin GQ. Room-temperature highly diastereoselective Zn-mediated allylation of chiral N-tert-butanesulfinyl imines: Remarkable reaction condition controlled stereoselectivity reversal[J]. Org. Lett.,2006,8(21):4979-4982.
APA	孙兴文,徐明华,&林国强.(2006).Room-temperature highly diastereoselective Zn-mediated allylation of chiral N-tert-butanesulfinyl imines: Remarkable reaction condition controlled stereoselectivity reversal.Org. Lett.,8(21),4979-4982.
MLA	孙兴文,et al."Room-temperature highly diastereoselective Zn-mediated allylation of chiral N-tert-butanesulfinyl imines: Remarkable reaction condition controlled stereoselectivity reversal".Org. Lett. 8.21(2006):4979-4982.