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	Continuous diode laser stimulated Raman gain/loss vibrational microscope
	ALFANO, ROBERT R.; SHI, LINGYAN; BUDANSKY, YURY
	2019-10-08
著作权人	ALFANO, ROBERT R.
专利号	US10433731
国家	美国
文献子类	授权发明
其他题名	Continuous diode laser stimulated Raman gain/loss vibrational microscope
英文摘要	There is a need for a compact instrument and microscope that maps the vibration fingerprints of biomolecules and chemicals in a sample such as brain, breast, cervix, and arteries. One can use spontaneous Raman scattering to accomplish this; however, the problem is low scattering efficiency to 10−5. With the availability of continuous wave diode laser at numerous wavelengths from 375 nm-1800 nm for parametric nonlinear difference vibrational mixing to enhance Stimulated Raman process within materials. A seed beam at Raman frequency is used with pump laser beam. In this way one can map in 2D and 3D images of the vibrations associate with disease changes. Scanning a pair of laser beams can map the location of vibrations within cells, smears, membranes, arteries, and tissues of animal and human.
公开日期	2019-10-08
申请日期	2016-08-22
状态	授权
内容类型	专利
源URL	[http://ir.opt.ac.cn/handle/181661/33144]
专题	半导体激光器专利数据库
作者单位	ALFANO, ROBERT R.
推荐引用方式 GB/T 7714	ALFANO, ROBERT R.,SHI, LINGYAN,BUDANSKY, YURY. Continuous diode laser stimulated Raman gain/loss vibrational microscope. US10433731. 2019-10-08.

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