The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process

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	The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process
	Sun W(孙伟); Sun W(孙伟); Xia CG(夏春谷)
刊名	Letters in Organic Chemistry
	2008
卷号	5 期号:8 页码:672-675
关键词	Deracemization oxidative agent Rhodotorula sp. AS2.2241 chemo-enzymatic one-pot secondary alcohols
ISSN号	1570-1786
通讯作者	夏春谷 ; 孙伟
中文摘要	Optically pure secondary alcohols were efficiently prepared via a two-step, one-pot process involving a chemical oxidative agent in combination with an enantioselective ketone reducase Rhodotorula sp. AS2.2241 in tandem. The reaction proceeded successfully with 88~99.5% enantiomeric excess in moderate to good conversions. A variety of substrates, including aromatic and aliphatic alcohols, could be tolerated.
学科主题	清洁催化与生物转化
收录类别	SCI
资助信息	the NSFC (20625308;20643008);Chinese Academy of Sciences
语种	英语
WOS记录号	WOS:000261926400014
公开日期	2012-12-04
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/2355]
专题	兰州化学物理研究所_OSSO国家重点实验室
通讯作者	Sun W(孙伟); Sun W(孙伟); Xia CG(夏春谷)
推荐引用方式 GB/T 7714	Sun W,Sun W,Xia CG. The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process[J]. Letters in Organic Chemistry,2008,5(8):672-675.
APA	孙伟,孙伟,&夏春谷.(2008).The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process.Letters in Organic Chemistry,5(8),672-675.
MLA	孙伟,et al."The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process".Letters in Organic Chemistry 5.8(2008):672-675.