Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum
	Cao, Mingming 1,2; Zhang, Yu1 ; He, Hongping 1; Li, Shifei 1,2; Huang, Shendian 1,2; Chen, Duozhi 1,2; Tang, Guihua1,2 ; Li, Shunlin 1; Di, Yingtong1 ; Hao, Xiaojiang1
刊名	JOURNAL OF NATURAL PRODUCTS
	2012-06-01
卷号	75 期号:6 页码:1076-1082
关键词	SKELETON CASCADE HUMILE ASSAY MIQ
ISSN号	0163-3864
英文摘要	Ten new yuzurine-type Daphniphyllum alkaloids, daphmacromines A-J (1-10), along with seven known alkaloids were isolated from the leaves and stems of Daphniphyllum macropodum. Their structures were elucidated by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry, and the structure of 1 was confirmed by single-crystal X-ray diffraction. The pesticidal and cytotoxic activities of the isolated alkaloids were evaluated in vitro against brine shrimp (Artemia sauna) and five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480), respectively. This study also suggested structural revisions of oxodaphnigracine, oxodaphnigraciline, and epioxodaphnigraciline.
类目[WOS]	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]	SKELETON ; CASCADE ; HUMILE ; ASSAY ; MIQ
收录类别	SCI ; IC
资助信息	National Natural Science Foundation of China [30830114, 31100259]; National Basic Research Program of China (973 Program) [2009CB522303, 2009CB940900]; Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047]
语种	英语
WOS记录号	WOS:000305503500011
公开日期	2012-11-30
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/15762]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Cao, Mingming,Zhang, Yu,He, Hongping,et al. Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(6):1076-1082.
APA	Cao, Mingming.,Zhang, Yu.,He, Hongping.,Li, Shifei.,Huang, Shendian.,...&Hao, Xiaojiang.(2012).Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum.JOURNAL OF NATURAL PRODUCTS,75(6),1076-1082.
MLA	Cao, Mingming,et al."Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum".JOURNAL OF NATURAL PRODUCTS 75.6(2012):1076-1082.