Noyori’s Ts-DPEN ligand: an efficient bifunctional primary amine-based organocatalyst in enantio- and diastereoselective Michael addition of 1,3-dicarbonyl indane compounds to nitroolefins

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	Noyori’s Ts-DPEN ligand: an efficient bifunctional primary amine-based organocatalyst in enantio- and diastereoselective Michael addition of 1,3-dicarbonyl indane compounds to nitroolefins
	Ju YD(鞠亚东); Xu LW(徐利文); Li L(李莉); Lai GQ(来国桥); Qiu HY(邱化玉); Jiang JX(蒋剑雄); Lu YX(卢一新)
刊名	Tetrahedron Letters
	2008
卷号	49 页码:6773-6777
关键词	Primary amine Dual activation Michael addition Organocatalysis
ISSN号	0040-4039
通讯作者	徐利文
中文摘要	Noyori’s Ts-DPEN ligand bearing an amino sulfonamide moiety and with a primary amino group on a chiral scaffold was found to be a simple and efficient bifunctional organocatalyst for the asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins, which gave highly functional Michael adduct with quaternary stereocenters in good enantioselectivities (up to 84%ee) and dr (up to 5.7:1 dr).
学科主题	物理化学
收录类别	SCI
资助信息	Hangzhou Normal University;the National Nature Science Foundation of China (Project No. 20572114)
语种	英语
公开日期	2012-11-09
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/1979]
专题	兰州化学物理研究所_OSSO国家重点实验室
推荐引用方式 GB/T 7714	Ju YD,Xu LW,Li L,et al. Noyori’s Ts-DPEN ligand: an efficient bifunctional primary amine-based organocatalyst in enantio- and diastereoselective Michael addition of 1,3-dicarbonyl indane compounds to nitroolefins[J]. Tetrahedron Letters,2008,49:6773-6777.
APA	Ju YD.,Xu LW.,Li L.,Lai GQ.,Qiu HY.,...&Lu YX.(2008).Noyori’s Ts-DPEN ligand: an efficient bifunctional primary amine-based organocatalyst in enantio- and diastereoselective Michael addition of 1,3-dicarbonyl indane compounds to nitroolefins.Tetrahedron Letters,49,6773-6777.
MLA	Ju YD,et al."Noyori’s Ts-DPEN ligand: an efficient bifunctional primary amine-based organocatalyst in enantio- and diastereoselective Michael addition of 1,3-dicarbonyl indane compounds to nitroolefins".Tetrahedron Letters 49(2008):6773-6777.