Using baicalin-functionalized magnetic nanoparticles for selectively extracting flavonoids from Rosa chinensis

	Using baicalin-functionalized magnetic nanoparticles for selectively extracting flavonoids from Rosa chinensis
	Qing, Lin-Sen ; Xiong, Jing ; Xue, Ying ; Liu, Yi-Ming ; Guang, Bin ; Ding, Li-Sheng ; Liao, Xun
刊名	JOURNAL OF SEPARATION SCIENCE
	2011
卷号	34 期号:22 页码:3240-3245
关键词	Baicalin ESI-MS MS Flavonoids Magnetic nanoparticles Solid-phase extraction
ISSN号	1615-9306
通讯作者	Liao, X (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Key Lab Mt Ecol Restorat & Bioresource Utilizat, Chengdu 610041, Peoples R China.
产权排序	1
英文摘要	An extraction agent featuring a natural product, baicalin, anchored on the surface of nanomagnetic particles (BMNPs) is herein reported. A facile solid-phase extraction (SPE) procedure with high selectivity toward flavonoids using BMNPs has been established. BMNPs were proven very effective for enriching flavonoids from extracts of medicinal plants such as Rosa chinensis. The SPE protocol involving a convenient solidliquid separation by using an external magnet field was easy to carry out. Further, the SPE sorbent (BMNPs) could be reused for many times reducing the operation cost. Importantly, flavonoids retained on the BMNPs were effectively recovered by eluting with methanol. Coupling the proposed SPE with ESI-MS/MS allowed a quick quantification of flavonoids in herbal extracts. Simultaneous determination of eight flavonoids extracted from R. chinensis was demonstrated in this work.
学科主题	Chemistry
收录类别	SCI
资助信息	National Natural Science Foundation of China[20872137, 21072184]
语种	英语
WOS记录号	WOS:000297949400017
公开日期	2012-11-09
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/23522]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Qing, Lin-Sen,Xiong, Jing,Xue, Ying,et al. Using baicalin-functionalized magnetic nanoparticles for selectively extracting flavonoids from Rosa chinensis[J]. JOURNAL OF SEPARATION SCIENCE,2011,34(22):3240-3245.
APA	Qing, Lin-Sen.,Xiong, Jing.,Xue, Ying.,Liu, Yi-Ming.,Guang, Bin.,...&Liao, Xun.(2011).Using baicalin-functionalized magnetic nanoparticles for selectively extracting flavonoids from Rosa chinensis.JOURNAL OF SEPARATION SCIENCE,34(22),3240-3245.
MLA	Qing, Lin-Sen,et al."Using baicalin-functionalized magnetic nanoparticles for selectively extracting flavonoids from Rosa chinensis".JOURNAL OF SEPARATION SCIENCE 34.22(2011):3240-3245.