Hollow Nanospheres Based on the Self-Assembly of Alginate-graft-poly(ethylene glycol) and alpha-Cyclodextrin

	Hollow Nanospheres Based on the Self-Assembly of Alginate-graft-poly(ethylene glycol) and alpha-Cyclodextrin
	Meng, Xian-Wei ; Ha, Wei ; Cheng, Cong ; Dong, Zhen-Qiang ; Ding, Li-Sheng ; Li, Bang-Jing ; Zhang, Sheng
刊名	LANGMUIR
	2011
卷号	27 期号:23 页码:14401-14407
ISSN号	0743-7463
通讯作者	Li, Bang-Jing ; Zhang, Sheng
产权排序	2
英文摘要	This article studies the self-assembly of alginate-graft-poly(ethylene glycol) (Alg-g-PEG) and alpha-cyclodextrin (alpha-CD) in aqueous solution. It was found that they could form hollow spheres because of the formation of coil-rod Alg-g-PEG/alpha-CD inclusion complexes. In these Alg-g-PEG/alpha-CD complexes, the alpha-CDs are stacked along the PEG side chains to form a rod block, and alginate main chains act as a coil block. More rod-like blocks in Alg-g-PEG/alpha-CD favor the formation of small assemblies. The assemblies of Alg-g-PEG/alpha-CD show a dependence on concentration, temperature, pH, and salt concentration. At low concentration (below 0.125%) or high temperature (above 32 degrees C), Alg-g-PEG/alpha-CD particles were unstable and disrupted. Increasing the salt or decreasing the pH resulted in the aggregation of Alg-g-mPEG/alpha-CD particles, as detected by the increase in the recorded hydrodynamic diameter (D-h).
学科主题	Chemistry; Materials Science
收录类别	SCI
资助信息	National Natural Science Foundation of China (NSFC)[51073107, 21074138, 50703025]; CAS[KSCX2-EW-J-22]; Ministry of Education of China[IRT1026]; State Key Laboratory of Polymer Materials Engineering (Sichuan University)[KF201003]
语种	英语
WOS记录号	WOS:000297427500055
公开日期	2012-11-09
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/23516]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Meng, Xian-Wei,Ha, Wei,Cheng, Cong,et al. Hollow Nanospheres Based on the Self-Assembly of Alginate-graft-poly(ethylene glycol) and alpha-Cyclodextrin[J]. LANGMUIR,2011,27(23):14401-14407.
APA	Meng, Xian-Wei.,Ha, Wei.,Cheng, Cong.,Dong, Zhen-Qiang.,Ding, Li-Sheng.,...&Zhang, Sheng.(2011).Hollow Nanospheres Based on the Self-Assembly of Alginate-graft-poly(ethylene glycol) and alpha-Cyclodextrin.LANGMUIR,27(23),14401-14407.
MLA	Meng, Xian-Wei,et al."Hollow Nanospheres Based on the Self-Assembly of Alginate-graft-poly(ethylene glycol) and alpha-Cyclodextrin".LANGMUIR 27.23(2011):14401-14407.