Localization of dopamine D1-receptor to A-type horizontal cells in the rabbit retina by single cell RT-PCR

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	Localization of dopamine D1-receptor to A-type horizontal cells in the rabbit retina by single cell RT-PCR
	Li, H ; Gaughwin, P ; Li, N ; He, SG
刊名	NEUROSCIENCE LETTERS
	2004
卷号	355 期号:40910 页码:146-148
关键词	dissociated retinal neurons nested PCR sequencing MAMMALIAN RETINA ENDOGENOUS DOPAMINE AMACRINE CELLS LIGHT MODULATION RELEASE ACID
ISSN号	0304-3940
通讯作者	He, SG (reprint author), Chinese Acad Sci, Inst Neurosci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China,s.he@ion.ac.cn
英文摘要	Dopamine is an important neurotransmitter regulating light-dark adaptation in the retina. The effect of dopamine is widespread and dependent on the localization of its receptors. We performed single cell RT-PCR on A-type horizontal cells visually selected from dissociated rabbit retinal neurons. Dopamine D1-receptor mRNA was positively identified. Subsequent sequencing of the fragment showed 82% homology with rat D1 receptor and 87% homology with human D1 receptor. This study supported previous observations that dopamine regulated A-type horizontal cell coupling via D1 receptors at the level of transcription. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
学科主题	Neurosciences & Neurology
收录类别	SCI
语种	英语
公开日期	2012-07-23
内容类型	期刊论文
源URL	[http://ir.sibs.ac.cn/handle/331001/1980]
专题	上海神经科学研究所_神经所(总)
推荐引用方式 GB/T 7714	Li, H,Gaughwin, P,Li, N,et al. Localization of dopamine D1-receptor to A-type horizontal cells in the rabbit retina by single cell RT-PCR[J]. NEUROSCIENCE LETTERS,2004,355(40910):146-148.
APA	Li, H,Gaughwin, P,Li, N,&He, SG.(2004).Localization of dopamine D1-receptor to A-type horizontal cells in the rabbit retina by single cell RT-PCR.NEUROSCIENCE LETTERS,355(40910),146-148.
MLA	Li, H,et al."Localization of dopamine D1-receptor to A-type horizontal cells in the rabbit retina by single cell RT-PCR".NEUROSCIENCE LETTERS 355.40910(2004):146-148.