Dopamine-mushroom body circuit regulates saliency-based decision-making in Drosophila

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	Dopamine-mushroom body circuit regulates saliency-based decision-making in Drosophila
	Zhang, Ke ; Guo, JianZeng ; Peng, Yueqing ; Xi, Wang ; Guo, Aike
刊名	SCIENCE
	2007
卷号	316 期号:5833 页码:1901-1904
关键词	EXPRESSION NEURONS BEHAVIOR MEMORY BRAIN MELANOGASTER VALUATION BODIES SYSTEM REWARD
ISSN号	0036-8075
通讯作者	Guo, AK (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Neurobiol, Inst Neurosci, 320 Yueyang Rd, Shanghai 200031, Peoples R China,akguo@ion.ac.cn
英文摘要	Drosophila melanogaster can make appropriate choices among alternative flight options on the basis of the relative salience of competing visual cues. We show that this choice behavior consists of early and late phases; the former requires activation of the dopaminergic system and mushroom bodies, whereas the latter is independent of these activities. Immunohistological analysis showed that mushroom bodies are densely innervated by dopaminergic axons. Thus, the circuit from the dopamine system to mushroom bodies is crucial for choice behavior in Drosophila.
学科主题	Science & Technology - Other Topics
收录类别	SCI
语种	英语
公开日期	2012-07-23
内容类型	期刊论文
源URL	[http://ir.sibs.ac.cn/handle/331001/1766]
专题	上海神经科学研究所_神经所(总)
推荐引用方式 GB/T 7714	Zhang, Ke,Guo, JianZeng,Peng, Yueqing,et al. Dopamine-mushroom body circuit regulates saliency-based decision-making in Drosophila[J]. SCIENCE,2007,316(5833):1901-1904.
APA	Zhang, Ke,Guo, JianZeng,Peng, Yueqing,Xi, Wang,&Guo, Aike.(2007).Dopamine-mushroom body circuit regulates saliency-based decision-making in Drosophila.SCIENCE,316(5833),1901-1904.
MLA	Zhang, Ke,et al."Dopamine-mushroom body circuit regulates saliency-based decision-making in Drosophila".SCIENCE 316.5833(2007):1901-1904.