Mekongenines A and B, two new alkaloids from Bousigonia mekongensis

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Mekongenines A and B, two new alkaloids from Bousigonia mekongensis
	Fu, Yanhui1,2 ; He, Hongping 1; Di, Yingtong1 ; Li, Shunlin 1; Zhang, Yu1 ; Hao, Xiaojiang1
刊名	TETRAHEDRON LETTERS
	2012-07-11
卷号	53 期号:28 页码:3642-3646
关键词	Bousigonia mekongensis Alkaloids Mekongenine A Mekongenine B
ISSN号	0040-4039
通讯作者	Zhang, Y (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China. ; zhangyu@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
英文摘要	Mekongenine A (1) possessing an unprecedented structure constituted from the union of a rare 2,7-seco eburnamine half and an aspidospermine alkaloid, together with a new bisindole alkaloid, mekongenine B (2), consisting of an eburnamine-aspidospennine type skeleton, was isolated from Bousigonia mekongensis. Their structures were elucidated by means of spectroscopic methods and those of 2 were further confirmed by X-ray diffraction. The absolute configurations of 1 and 2 were determined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra. Mekongenines A (1) and B(2) exhibited cell growth inhibitory activities against various human cancer cell lines. (C) 2012 Elsevier Ltd. All rights reserved.
学科主题	Chemistry, Organic
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	MELODINUS-HENRYI ; CHINENSIS
收录类别	SCI ; IC
资助信息	National Natural Science Foundation of China[31100259, 30830114]; National Basic Research Program of China[2009CB940900, 2009CB522303]; Young Academic and Technical Leader Raising Foundation of Yunnan Province[2009CI072]
语种	英语
WOS记录号	WOS:000305856100025
公开日期	2012-09-03
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/15077]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Fu, Yanhui,He, Hongping,Di, Yingtong,et al. Mekongenines A and B, two new alkaloids from Bousigonia mekongensis[J]. TETRAHEDRON LETTERS,2012,53(28):3642-3646.
APA	Fu, Yanhui,He, Hongping,Di, Yingtong,Li, Shunlin,Zhang, Yu,&Hao, Xiaojiang.(2012).Mekongenines A and B, two new alkaloids from Bousigonia mekongensis.TETRAHEDRON LETTERS,53(28),3642-3646.
MLA	Fu, Yanhui,et al."Mekongenines A and B, two new alkaloids from Bousigonia mekongensis".TETRAHEDRON LETTERS 53.28(2012):3642-3646.