Three New Terpenoid Indole Alkaloids from Catharanthus roseus

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Three New Terpenoid Indole Alkaloids from Catharanthus roseus
	Wang, Lei1,2 ; Zhang, Yu1 ; He, Hong-Ping 1; Zhang, Qiang 1; Li, Shi-Fei 1,2; Hao, Xiao-Jiang1
刊名	PLANTA MEDICA
	2011-05-01
卷号	77 期号:7 页码:754-758
关键词	Catharanthus roseus (L.) G. Don Apocynaceae terpenoid indole alkaloids vidolicine normacusine B N-oxide lochnerine N-oxide cytotoxic activity
ISSN号	0032-0943
通讯作者	Hao, XJ (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
英文摘要	Three new terpenoid indole alkaloids, vidolicine (1), normacusine B N-oxide (2), and lochnerine N-oxide (3), together with seven known ones (410), were isolated from whole plants of Catharanthus roseus. Their structures were elucidated by spectroscopic methods (NMR, MS, UV, and IR). Cytotoxic activities of these isolates (1-10) were evaluated, but only compound 8 was active against HL-60, SMMC-7721, and A549 cell lines.
学科主题	Plant Sciences; Pharmacology & Pharmacy
类目[WOS]	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]	LEAVES
收录类别	SCI
资助信息	Ministry of Science and Technology[2009CB940900, 2009CB522300]; National Natural Science Foundation of China[30830114]
语种	英语
WOS记录号	WOS:000290303200013
公开日期	2012-07-18
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/13563]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wang, Lei,Zhang, Yu,He, Hong-Ping,et al. Three New Terpenoid Indole Alkaloids from Catharanthus roseus[J]. PLANTA MEDICA,2011,77(7):754-758.
APA	Wang, Lei,Zhang, Yu,He, Hong-Ping,Zhang, Qiang,Li, Shi-Fei,&Hao, Xiao-Jiang.(2011).Three New Terpenoid Indole Alkaloids from Catharanthus roseus.PLANTA MEDICA,77(7),754-758.
MLA	Wang, Lei,et al."Three New Terpenoid Indole Alkaloids from Catharanthus roseus".PLANTA MEDICA 77.7(2011):754-758.