Composite of CdTe quantum dots and molecularly imprinted polymer as a sensing material for cytochrome c

	Composite of CdTe quantum dots and molecularly imprinted polymer as a sensing material for cytochrome c
	Zhang, Wei 1; He, Xi-Wen 1; Chen, Yang 1; Li, Wen-You 1; Zhang, Yu-Kui 1,2
刊名	biosensors & bioelectronics
	2011-01-15
卷号	26 期号:5 页码:2553-2558
关键词	Imprinting Quantum dots Sensing material Cytochrome c Recognition
ISSN号	待补充
通讯作者	李文友
产权排序	2,5
中文摘要	composite of cdte quantum dots and molecularly imprinted polymer as a sensing material for cytochrome c
英文摘要	a newly designed molecularly imprinted polymer (mip) material was fabricated and successfully utilized as recognition element to develop a quantum dots (qds) based mip-coated composite for selective recognition of the template cytochrome c (cyt). the composites were synthesized by sol-gel reaction (imprinting process). the imprinting process resulted in an increased affinity of the composites toward the corresponding template. the fluorescence of mip-coated qds was stronger quenched by the template versus that of non-imprinted polymer (nip)-coated qds, which indicated the composites could recognize the corresponding template. the results of specific experiments further exhibited the recognition ability of the composites. under optimum conditions, the linear range for cyt is from 0.97 mu m to 24 mu m, and the detection limit is 0.41 mu m. the new composites integrated the high selectivity of molecular imprinting technology and fluorescence property of qds and could convert the specific interactions between imprinted cavities and corresponding template to the obvious changes of fluorescence signal. therefore, a simple and selective sensing system for protein recognition has been realized. (c) 2010 elsevier b.v. all rights reserved.
学科主题	物理化学
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biophysics ; biotechnology & applied microbiology ; chemistry, analytical ; electrochemistry ; nanoscience & nanotechnology
研究领域[WOS]	biophysics ; biotechnology & applied microbiology ; chemistry ; electrochemistry ; science & technology - other topics
关键词[WOS]	recognition ; nanocrystals ; fluorescence ; sensor ; photoluminescence ; nanoparticles ; biomolecules ; proteins ; antibody ; system
收录类别	SCI
语种	英语
WOS记录号	WOS:000286904400123
公开日期	2012-07-09
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/115330]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116011, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Wei,He, Xi-Wen,Chen, Yang,et al. Composite of CdTe quantum dots and molecularly imprinted polymer as a sensing material for cytochrome c[J]. biosensors & bioelectronics,2011,26(5):2553-2558.
APA	Zhang, Wei,He, Xi-Wen,Chen, Yang,Li, Wen-You,&Zhang, Yu-Kui.(2011).Composite of CdTe quantum dots and molecularly imprinted polymer as a sensing material for cytochrome c.biosensors & bioelectronics,26(5),2553-2558.
MLA	Zhang, Wei,et al."Composite of CdTe quantum dots and molecularly imprinted polymer as a sensing material for cytochrome c".biosensors & bioelectronics 26.5(2011):2553-2558.