Recent advances in micro-scale and nano-scale high-performance liquid-phase chromatography for proteome research
Tao, Dingyin1,2; Zhang, Lihua1; Shan, Yichu1; Liang, Zhen1; Zhang, Yukui1
刊名analytical and bioanalytical chemistry
2011
卷号399期号:1页码:229-241
关键词Proteome Micro-HPLC Nano-HPLC Multi-dimensional separation MS-MS
ISSN号待补充
通讯作者张丽华
产权排序1,1
中文摘要recent advances in micro-scale and nano-scale high-performance liquid-phase chromatography for proteome research
英文摘要high-performance liquid chromatography-electrospray ionization tandem mass spectrometry (hplc-esi-ms-ms) is regarded as one of the most powerful techniques for separation and identification of proteins. recently, much effort has been made to improve the separation capacity, detection sensitivity, and analysis throughput of micro- and nano-hplc, by increasing column length, reducing column internal diameter, and using integrated techniques. development of hplc columns has also been rapid, as a result of the use of submicrometer packing materials and monolithic columns. all these innovations result in clearly improved performance of micro- and nano-hplc for proteome research.
学科主题物理化学
WOS标题词science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]biochemical research methods ; chemistry, analytical
研究领域[WOS]biochemistry & molecular biology ; chemistry
关键词[WOS]tandem mass-spectrometry ; maldi-tof-ms ; size-exclusion chromatography ; human liver-tissue ; reversed-phase ; monolithic columns ; electrospray-ionization ; shotgun proteomics ; esi-ms/ms ; multidimensional separations
收录类别SCI
语种英语
WOS记录号WOS:000285781200024
公开日期2012-07-09
内容类型期刊论文
源URL[http://159.226.238.44/handle/321008/115319]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Natl Chromatog R&A Ctr, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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GB/T 7714
Tao, Dingyin,Zhang, Lihua,Shan, Yichu,et al. Recent advances in micro-scale and nano-scale high-performance liquid-phase chromatography for proteome research[J]. analytical and bioanalytical chemistry,2011,399(1):229-241.
APA Tao, Dingyin,Zhang, Lihua,Shan, Yichu,Liang, Zhen,&Zhang, Yukui.(2011).Recent advances in micro-scale and nano-scale high-performance liquid-phase chromatography for proteome research.analytical and bioanalytical chemistry,399(1),229-241.
MLA Tao, Dingyin,et al."Recent advances in micro-scale and nano-scale high-performance liquid-phase chromatography for proteome research".analytical and bioanalytical chemistry 399.1(2011):229-241.
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