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	Phenols with Anti-HIV Activity from Daphne acutiloba
	Huang, Sheng Zhuo1,4; Zhang, Xing Jie3,4; Li, Xing Yao3,4; Jiang, He Zhong1,4; Ma, Qing Yun2; Wang, Peng Cheng1,4; Liu, Yu Qing1; Hu, Jiang Miao1; Zheng, Yong Tang3; Zhou, Jun1
刊名	PLANTA MEDICA
	2012
卷号	78期号:2页码:182-185
关键词	Daphne acutiloba Thymelaeceae anti-HIV activity phenols
ISSN号	0032-0943
通讯作者	Zhou, J (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China, jzhou@mail.kib.ac.cn ; zhaoyx1011@163.com
英文摘要	The present paper describes the study of the phytochemical properties and anti-HIV activity of the phenolic isolates of the plateau medicinal plant Daphne acutiloba Rehd. (Thymelaeceae). Two new lignans named daphnenin (1) and daphnetone (2), along with 11 known ones, were isolated, and their structures were elucidated by 1D and 2D NMR spectroscopy as well as HR-E-SI-MS. In the anti-HIV activity study, daphnenin (1) and caffeic acid n-octadecyl ester (13) showed definite anti-HIV activity with EC50 values of 0.39 and 0.16 mu g/mL, respectively.
学科主题	Plant Sciences; Chemistry ; Medicinal; Pharmacology & Pharmacy
类目[WOS]	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]	LIGNANS ; CONSTITUENTS
收录类别	SCI
资助信息	National Nonprofit Institute Research Grant of CATAS-ITBB[110301]; Natural Science Foundation of Yunnan[2008CD159]
语种	英语
WOS记录号	WOS:000299909300014
公开日期	2012-06-07
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/10383]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650204, Peoples R China 4.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Huang, Sheng Zhuo,Zhang, Xing Jie,Li, Xing Yao,et al. Phenols with Anti-HIV Activity from Daphne acutiloba[J]. PLANTA MEDICA,2012,78(2):182-185.
APA	Huang, Sheng Zhuo.,Zhang, Xing Jie.,Li, Xing Yao.,Jiang, He Zhong.,Ma, Qing Yun.,...&Zhao, You Xing.(2012).Phenols with Anti-HIV Activity from Daphne acutiloba.PLANTA MEDICA,78(2),182-185.
MLA	Huang, Sheng Zhuo,et al."Phenols with Anti-HIV Activity from Daphne acutiloba".PLANTA MEDICA 78.2(2012):182-185.

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