MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE

	MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE
	Wang H ; Song HR ; Cui Y ; Deng YJ ; Chen XS
刊名	chinese journal of polymer science
	2011
卷号	29 期号:2 页码:173-179
关键词	BIOMEDICAL APPLICATIONS BLOCK-COPOLYMERS FIBERS GLYCOL) ACID)
ISSN号	0256-7679
通讯作者	deng yj
中文摘要	ultra-fine fibrous mats with magnolol entrapped have been prepared by electrospinning biodegradable copolymer poly(ethylene glycol) blocked poly(l-lactide). drug entrapment was perfect which was confirmed by scanning electron microscopy and differential scanning calorimetry. according to in vitro drug release investigation by high performance liquid chromatography, it was found that fibers with 10%, 20% and 30% drug entrapped respect to polymer (mass ratio) presented dramatically different drug release behavior and degradation behavior under the effect of proteinase k. the reason may be that fibers with 10% drug entrapped was more easily affected by enzyme while, to some degree, magnolol in fibers with 20% and 30% entrapped prevented polymer from being degraded by enzyme.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000289167200006
公开日期	2012-06-12
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/45019]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Wang H,Song HR,Cui Y,et al. MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE[J]. chinese journal of polymer science,2011,29(2):173-179.
APA	Wang H,Song HR,Cui Y,Deng YJ,&Chen XS.(2011).MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE.chinese journal of polymer science,29(2),173-179.
MLA	Wang H,et al."MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE".chinese journal of polymer science 29.2(2011):173-179.