MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE | |
Wang H ; Song HR ; Cui Y ; Deng YJ ; Chen XS | |
刊名 | chinese journal of polymer science
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2011 | |
卷号 | 29期号:2页码:173-179 |
关键词 | BIOMEDICAL APPLICATIONS BLOCK-COPOLYMERS FIBERS GLYCOL) ACID) |
ISSN号 | 0256-7679 |
通讯作者 | deng yj |
中文摘要 | ultra-fine fibrous mats with magnolol entrapped have been prepared by electrospinning biodegradable copolymer poly(ethylene glycol) blocked poly(l-lactide). drug entrapment was perfect which was confirmed by scanning electron microscopy and differential scanning calorimetry. according to in vitro drug release investigation by high performance liquid chromatography, it was found that fibers with 10%, 20% and 30% drug entrapped respect to polymer (mass ratio) presented dramatically different drug release behavior and degradation behavior under the effect of proteinase k. the reason may be that fibers with 10% drug entrapped was more easily affected by enzyme while, to some degree, magnolol in fibers with 20% and 30% entrapped prevented polymer from being degraded by enzyme. |
收录类别 | SCI收录期刊论文 |
语种 | 英语 |
WOS记录号 | WOS:000289167200006 |
公开日期 | 2012-06-12 |
内容类型 | 期刊论文 |
源URL | [http://ir.ciac.jl.cn/handle/322003/45019] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Wang H,Song HR,Cui Y,et al. MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE[J]. chinese journal of polymer science,2011,29(2):173-179. |
APA | Wang H,Song HR,Cui Y,Deng YJ,&Chen XS.(2011).MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE.chinese journal of polymer science,29(2),173-179. |
MLA | Wang H,et al."MAGNOLOL ENTRAPPED ULTRA-FINE FIBROUS MATS ELECTROSPUN FROM POLY(ETHYLENE GLYCOL)-b-POLY(L-LACTIDE) AND IN VITRO RELEASE".chinese journal of polymer science 29.2(2011):173-179. |
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