Genomewide Analysis of Carotenoid Cleavage Dioxygenases in Unicellular and Filamentous Cyanobacteria

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	Genomewide Analysis of Carotenoid Cleavage Dioxygenases in Unicellular and Filamentous Cyanobacteria
	Cui, Hongli 1,2; Wang, Yinchu1,2 ; Qin, Song1
刊名	COMPARATIVE AND FUNCTIONAL GENOMICS
	2012
期号	.页码:164690
关键词	IN-VITRO CHARACTERIZATION NOSTOC SP PCC-7120 ABSCISIC-ACID SWISS-MODEL BIOCHEMICAL-CHARACTERIZATION SUBSTRATE-SPECIFICITY RETINAL BIOSYNTHESIS OXIDATIVE CLEAVAGE CROCUS-SATIVUS YELLOW PIGMENT
ISSN号	1531-6912
通讯作者	Qin, S (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Coastal Zonebio Resource Lab, Yantai 264003, Peoples R China. sqin@yic.ac.cn
产权排序	[Cui, Hongli; Wang, Yinchu; Qin, Song] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Coastal Zonebio Resource Lab, Yantai 264003, Peoples R China; [Cui, Hongli; Wang, Yinchu] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Grad Univ, Beijing 100049, Peoples R China
中文摘要	Carotenoid cleavage dioxygenases (CCDs) are a group of enzymes that catalyze the oxidative cleavage steps from carotenoids to various carotenoid cleavage products. Some ccd genes have been identified and encoded enzymes functionally characterized in many higher plants, but little in cyanobacteria. We performed a comparative analysis of ccd sequences and explored their distribution, classification, phylogeny, evolution, and structure among 37 cyanobacteria. Totally 61 putative ccd sequences were identified, which are abundant in Acaryochloris marina MBIC 11017, filamentous N-2-fixing cyanobacteria, and unicellular cyanobacterial Cyanothece. According to phylogenetic trees of 16S rDNA and CCD, nced and ccd8 genes occur later than the divergence of ccd7, apco, and ccd1. All CCD enzymes share conserved basic structure domains constituted by a single loop formed with seven beta-strands and one helix. In this paper, a general framework of sequence-function-evolution connection for the ccd has been revealed, which may provide new insight for functional investigation.
英文摘要	Carotenoid cleavage dioxygenases (CCDs) are a group of enzymes that catalyze the oxidative cleavage steps from carotenoids to various carotenoid cleavage products. Some ccd genes have been identified and encoded enzymes functionally characterized in many higher plants, but little in cyanobacteria. We performed a comparative analysis of ccd sequences and explored their distribution, classification, phylogeny, evolution, and structure among 37 cyanobacteria. Totally 61 putative ccd sequences were identified, which are abundant in Acaryochloris marina MBIC 11017, filamentous N-2-fixing cyanobacteria, and unicellular cyanobacterial Cyanothece. According to phylogenetic trees of 16S rDNA and CCD, nced and ccd8 genes occur later than the divergence of ccd7, apco, and ccd1. All CCD enzymes share conserved basic structure domains constituted by a single loop formed with seven beta-strands and one helix. In this paper, a general framework of sequence-function-evolution connection for the ccd has been revealed, which may provide new insight for functional investigation.
学科主题	Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology; Genetics & Heredity
研究领域[WOS]	Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Genetics & Heredity
关键词[WOS]	IN-VITRO CHARACTERIZATION ; NOSTOC SP PCC-7120 ; ABSCISIC-ACID ; SWISS-MODEL ; BIOCHEMICAL-CHARACTERIZATION ; SUBSTRATE-SPECIFICITY ; RETINAL BIOSYNTHESIS ; OXIDATIVE CLEAVAGE ; CROCUS-SATIVUS ; YELLOW PIGMENT
收录类别	SCI
资助信息	National Natural Science Foundation of China[40876082]; Chinese Academy of Sciences; Outstanding Young Scholars Fellowship of Shandong Province[JQ200914]
原文出处	http://www.hindawi.com/journals/cfg/2012/164690/
语种	英语
WOS记录号	WOS:000301263900001
公开日期	2012-06-13
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/5556]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Coastal Zonebio Resource Lab, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Cui, Hongli,Wang, Yinchu,Qin, Song. Genomewide Analysis of Carotenoid Cleavage Dioxygenases in Unicellular and Filamentous Cyanobacteria[J]. COMPARATIVE AND FUNCTIONAL GENOMICS,2012(.):164690.
APA	Cui, Hongli,Wang, Yinchu,&Qin, Song.(2012).Genomewide Analysis of Carotenoid Cleavage Dioxygenases in Unicellular and Filamentous Cyanobacteria.COMPARATIVE AND FUNCTIONAL GENOMICS(.),164690.
MLA	Cui, Hongli,et al."Genomewide Analysis of Carotenoid Cleavage Dioxygenases in Unicellular and Filamentous Cyanobacteria".COMPARATIVE AND FUNCTIONAL GENOMICS ..(2012):164690.