Dual-Emission Fluorescent Silica Nanoparticle-Based Probe for Ultrasensitive Detection of Cu(2+)

	Dual-Emission Fluorescent Silica Nanoparticle-Based Probe for Ultrasensitive Detection of Cu(2+)
	Zong CH ; Ai KL ; Zhang G ; Li HW ; Lu LH
刊名	analytical chemistry
	2011
卷号	83 期号:8 页码:3126-3132
关键词	ATOMIC-ABSORPTION SPECTROMETER TRANSITION-METAL IONS CDS QUANTUM DOTS COMPLEX-FORMATION AQUEOUS-SOLUTION LIVING CELLS COPPER IONS SENSOR ULTRAFILTRATION POLYETHYLENEIMINE
ISSN号	0003-2700
通讯作者	lu lh
中文摘要	an effective dual-emission fluorescent silica nanoparticle-based probe has been constructed for rapid and ultrasensitive detection of cu(2+). in this nanoprobe, a dye-doped silica cote served as a reference signal, thus providing a built-in correction for environmental effects. a response dye was covalently grafted on the surface of the silica nanoparticles through a chelating reagent for cu(2+). the fluorescence of the response dye could be selectively quenched in the presence of cu(2+) accompanied by a visual orange-to-green color switch of the nanoprobe. the nanoprobe provided an effective platform for reliable detection of cu(2+) with a detection limit as low as 10 nm, which is nearly 2 x 10(3) times lower than the maximum level (similar to 20 mu m) of cu(2+) in drinking water permitted by the u.s. environmental protection agency (epa). the high sensitivity was attributed to the strong chelation of cu(2+) with polyethyleneimine (pei) and a signal amplification effect. the nanoprobe constructed by this method was very stable, enabling the rapid detection of cu(2+) in real water samples. good linear correlations were obtained over the concentration range from 1 x 10(-7) to 8 x 10(-7) (r(2) = 0.99) with recoveries of 103.8-99.14% and 95.5-95.14% for industrial wastewater and lake water, respectively. additionally, the long-wavelength emission of the response dye can avoid the interference of the autofluorescence of the biosystems, which facilitated their applications in monitoring cu(2+) in cells. furthermore, the nanoprobe showed a good reversibility; the fluorescence can be switched "off' and "on" by an addition of cu(2+) and edta, respectively.
收录类别	SCI收录期刊论文
语种	英语
公开日期	2012-06-11
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/44702]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Zong CH,Ai KL,Zhang G,et al. Dual-Emission Fluorescent Silica Nanoparticle-Based Probe for Ultrasensitive Detection of Cu(2+)[J]. analytical chemistry,2011,83(8):3126-3132.
APA	Zong CH,Ai KL,Zhang G,Li HW,&Lu LH.(2011).Dual-Emission Fluorescent Silica Nanoparticle-Based Probe for Ultrasensitive Detection of Cu(2+).analytical chemistry,83(8),3126-3132.
MLA	Zong CH,et al."Dual-Emission Fluorescent Silica Nanoparticle-Based Probe for Ultrasensitive Detection of Cu(2+)".analytical chemistry 83.8(2011):3126-3132.