Collagen/apatite coating on 3-dimensional carbon/carbon composite

CORC > 金属研究所 > 中国科学院金属研究所

	Collagen/apatite coating on 3-dimensional carbon/carbon composite
	S. H. Li ; Z. G. Zheng ; Q. Liu ; J. R. de Wijn ; K. de Groot
刊名	Journal of Biomedical Materials Research
	1998
卷号	40 期号:4 页码:520-529
关键词	3D carbon/carbon composite collagen/apatite composite coating grafting phosphorylation calcium-phosphate growth cotton
ISSN号	0021-9304
中文摘要	A three-dimensional carbon/carbon composite (3D C/C) was studied as potential bone-repairing material; its major mechanical properties were found to be closer to those of human bone than other common bone-repairing materials available. In vitro calcification tests revealed that as-received 3D C/C is almost bioinert in simulated body fluid (SBF) over an immersion period of 4 weeks. To improve the bioactivity of 3D C/C, surface modification was accomplished through two practical routes: (1) grafting with polyethylene glycol (PEG) and (2) phosphorylation and precalcification. After grafting with alpha, omega di(aminopropyl) polyethylene glycol 800 (NH2-PEG-NH2), a continuous layer of calcium phosphate was formed on the surface of 3D C/C in SBF after 4 weeks. Phosphorylated 3D C/C samples have the ability to induce apatite precipitation after precalcification in a saturated Ca(OH)(2) solution for 1 week. To speed up the coating process, a calcification solution with collagen was developed in which a collagen/apatite coating layer can be formed on 3D C/C in 9 h in ambient conditions. (C) 1998 John Wiley & Sons, Inc.
原文出处	://WOS:000073465000002
公开日期	2012-04-14
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/37705]
专题	金属研究所_中国科学院金属研究所
推荐引用方式 GB/T 7714	S. H. Li,Z. G. Zheng,Q. Liu,et al. Collagen/apatite coating on 3-dimensional carbon/carbon composite[J]. Journal of Biomedical Materials Research,1998,40(4):520-529.
APA	S. H. Li,Z. G. Zheng,Q. Liu,J. R. de Wijn,&K. de Groot.(1998).Collagen/apatite coating on 3-dimensional carbon/carbon composite.Journal of Biomedical Materials Research,40(4),520-529.
MLA	S. H. Li,et al."Collagen/apatite coating on 3-dimensional carbon/carbon composite".Journal of Biomedical Materials Research 40.4(1998):520-529.