Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions

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	Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions
	T. Hou ; J. Z. Zhang ; L. J. Kong ; X. F. Zhang ; P. Hu ; D. M. Zhang ; N. Li
刊名	Journal of Biomaterials Science-Polymer Edition
	2006
卷号	17 期号:7 页码:735-746
关键词	tissue engineering ion implantation cell culture bioactivity cross-linking 3-dimensional scaffolds tissue regeneration dermal substitute collagen polyhydroxyalkanoates gelatin reconstruction polyethylene replacement
ISSN号	0920-5063
中文摘要	Polyhydroxybutyrate (PHB) films were implanted with 40 keV hydroxyl ions with fluences ranging from 1 X 10(12) to 1 X 10(15) ions/cm2, respectively. The as-implanted PHB films were characterized by scanning electron microscopy (SEM), electron spectroscopy for chemical analysis (ESCA) and water contact angle measurements. The surface structures and properties of the as-implanted PHB films were closely related with hydroxyl ion fluence. They were further investigated by inoculating 3T6 fibroblasts cells on their surfaces. Morphologies of the 3T6 fibroblast cells cultured on surfaces of the as-implanted PHB films were observed by SEM. Characterization of the cultural 3T6 cells was analyzed qualitatively. The preliminary experimental results reveal that the bioactivity of the PHB films modified by hydroxyl ion implantation was improved at different levels, and the fluence of 1 X 10(13) ionS/cm(2) is optimal for PHB film.
原文出处	://WOS:000239480000002
公开日期	2012-04-13
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/34243]
专题	金属研究所_中国科学院金属研究所
推荐引用方式 GB/T 7714	T. Hou,J. Z. Zhang,L. J. Kong,et al. Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions[J]. Journal of Biomaterials Science-Polymer Edition,2006,17(7):735-746.
APA	T. Hou.,J. Z. Zhang.,L. J. Kong.,X. F. Zhang.,P. Hu.,...&N. Li.(2006).Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions.Journal of Biomaterials Science-Polymer Edition,17(7),735-746.
MLA	T. Hou,et al."Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions".Journal of Biomaterials Science-Polymer Edition 17.7(2006):735-746.