The preparation, cytocompatibility, and in vitro biodegradation study of pure beta-TCP on magnesium

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	The preparation, cytocompatibility, and in vitro biodegradation study of pure beta-TCP on magnesium
	F. Geng ; L. L. Tan ; X. X. Jin ; J. Y. Yang ; K. Yang
刊名	Journal of Materials Science-Materials in Medicine
	2009
卷号	20 期号:5 页码:1149-1157
关键词	simulated body-fluid corrosion behavior phosphate ceramics composite coatings microwave irradiation tricalcium phosphate bond strength hydroxyapatite titanium alloys
ISSN号	0957-4530
中文摘要	Biodegradable and bioactive beta-tricalcium phosphate (beta-TCP) coatings were prepared on magnesium (Mg) in order to improve its biocompatibility by a chemical method. The tensile bonding strength of beta-TCP coating and Mg substrate was measured by the standard adhesion test (ISO 13779-4). And the cytocompatibility of beta-TCP coated Mg was studied by using human osteoblast-like MG63 cells. It was found that the MG63 cells could grow well on the surface of beta-TCP coated Mg and the cell viability on beta-TCP coated Mg was above 80% during the cocultivation of MG63 cells and beta-TCP coated Mg for 10 days, indicating no cytotoxicity. It was concluded that the beta-TCP coated Mg had good cytocompatibility. The degradation of Mg substrate with beta-TCP coating in vitro was studied in detail by XRD, EDX, SEM, and ICP. The results showed that a bone-like apatite continually formed on the surface of the sample with the degradation of both Mg substrate and beta-TCP coating in Hank's solution (a simulated body fluid). The biodegradation mechanism was preliminarily analyzed in the paper.
原文出处	://WOS:000264837700015
公开日期	2012-04-13
内容类型	期刊论文
源URL	[http://210.72.142.130/handle/321006/31930]
专题	金属研究所_中国科学院金属研究所
推荐引用方式 GB/T 7714	F. Geng,L. L. Tan,X. X. Jin,et al. The preparation, cytocompatibility, and in vitro biodegradation study of pure beta-TCP on magnesium[J]. Journal of Materials Science-Materials in Medicine,2009,20(5):1149-1157.
APA	F. Geng,L. L. Tan,X. X. Jin,J. Y. Yang,&K. Yang.(2009).The preparation, cytocompatibility, and in vitro biodegradation study of pure beta-TCP on magnesium.Journal of Materials Science-Materials in Medicine,20(5),1149-1157.
MLA	F. Geng,et al."The preparation, cytocompatibility, and in vitro biodegradation study of pure beta-TCP on magnesium".Journal of Materials Science-Materials in Medicine 20.5(2009):1149-1157.