Effects of Ti2448 half-pin with low elastic modulus on pin loosening in unilateral external fixation | |
K. Zheng ; X. K. Li ; J. Fu ; X. L. Fan ; P. Wang ; Y. L. Hao ; S. J. Li ; H. B. Fan ; Z. Guo | |
刊名 | Journal of Materials Science-Materials in Medicine
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2011 | |
卷号 | 22期号:6页码:1579-1588 |
关键词 | skeletal fixation stainless-steel tract infection schanz screws bone complications strength fractures interface movement |
ISSN号 | 0957-4530 |
中文摘要 | The objective of this study was to compare the benefits of titanium 2448 (Ti2448) half-pin and titanium-6 aluminium-4 vanadium (TAV) half-pin on reducing pin loosening during external fracture fixation. Although having similar strength, Ti2448 half-pin had even lower elastic modules(33 GPa) when compared with TAV half-pin (110 GPa), which was similar to that of cortical bone (20 GPa). In the external fixation of tibial model fractures and canine cadaveric tibia fractures, Ti2448 half-pin had greater recoverable deformation and less stress concentration at the pin-bone interface in compression, torsion, and four-points bending test. Then, tibial fractures were created in 24 dogs and stabilized with four half-pins of either Ti2448 or TAV in each animal. At 4 and 8 weeks post-operatively, fracture healing and pin loosening was assessed by radiographic grading scale. The scores of Ti2448 group were significantly higher than those of TAV group. Micro-CT analysis also indicated larger quantity and higher quality of newly formed bone at pin-bone interface in Ti2448 group. Histology observation showed the newly formed bone integrated well into the threads of Ti2448 half-pins. In contrast, there was a layer of necrotic tissue between the bone tissue and TAV half-pin at pin-bone interface in TAV group. The extraction torque values of Ti2448 half-pins near the fracture line were significantly higher than those TAV pins. In conclusion, the Ti2448 half-pin with low elastic modulus could enhance osseointegration and reduce pin loosening when compared with TAV half-pin. It is a promising biomaterial for constructing external fixation system in clinical application. |
原文出处 | |
公开日期 | 2012-04-13 |
内容类型 | 期刊论文 |
源URL | [http://210.72.142.130/handle/321006/30963] ![]() |
专题 | 金属研究所_中国科学院金属研究所 |
推荐引用方式 GB/T 7714 | K. Zheng,X. K. Li,J. Fu,et al. Effects of Ti2448 half-pin with low elastic modulus on pin loosening in unilateral external fixation[J]. Journal of Materials Science-Materials in Medicine,2011,22(6):1579-1588. |
APA | K. Zheng.,X. K. Li.,J. Fu.,X. L. Fan.,P. Wang.,...&Z. Guo.(2011).Effects of Ti2448 half-pin with low elastic modulus on pin loosening in unilateral external fixation.Journal of Materials Science-Materials in Medicine,22(6),1579-1588. |
MLA | K. Zheng,et al."Effects of Ti2448 half-pin with low elastic modulus on pin loosening in unilateral external fixation".Journal of Materials Science-Materials in Medicine 22.6(2011):1579-1588. |
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