In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment

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	In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment
	X. Han ; H. C. Liu ; D. S. Wang ; S. J. Li ; R. Yang ; X. J. Tao ; X. H. Jiang
刊名	Journal of Materials Science & Technology
	2011
卷号	27 期号:4 页码:317-324
关键词	Titanium alloy Micro-arc oxidation Alkali heatment MC3T3-E1 cells In vitro cell response apatite-forming ability surface modification titanium surfaces cell-attachment ti implants metal roughness films water
ISSN号	1005-0302
中文摘要	The purpose of this study was to test the hypothesis that the combination of micro-arc oxidation and alkali heatment (MAH) would improve the cytocompatibility of a newly designed Ti-24Nb-4Zr-8Sn alloy. In this study, commercially pure titanium (cp Ti) and Ti-24Nb-4Zr-8Sn were used. Surface modification of Ti-24Nb-4Zr-8Sn by a two-step treatment of micro-arc oxidation (MAO) and alkali heatment was reported. Surface characterizations were performed by scanning electron microscopy (SEM), thin film X-ray diffraction (TF-XRD) and X-ray photoelectron spectroscopy (XPS). The MAH layer consisted of finer crystals and possessed a higher degree of crystallity and stability than the MAO layer. A biocompatibility study on treated and untreated Ti-24Nb-4Zr-8Sn in comparison with cp Ti was carried out to investigate the effect of the different surfaces on the bone integration property in vitro. The cellular assays revealed that the MAO and MAH layer favored the initial adhesion of MC3T3-E1 cells and that the growth rate of MC3T3-E1 cells on MAH layer was significantly higher than that on the conventional MAO-treated layer after 3-day and 5-day incubation, demonstrating the greater potential of the hybrid treatment of micro-arc oxidation followed with alkali heatment as a novel surface modification method for implanting materials.
原文出处	://WOS:000290592200005
公开日期	2012-04-13
内容类型	期刊论文
源URL	[http://210.72.142.130/handle/321006/30374]
专题	金属研究所_中国科学院金属研究所
推荐引用方式 GB/T 7714	X. Han,H. C. Liu,D. S. Wang,et al. In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment[J]. Journal of Materials Science & Technology,2011,27(4):317-324.
APA	X. Han.,H. C. Liu.,D. S. Wang.,S. J. Li.,R. Yang.,...&X. H. Jiang.(2011).In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment.Journal of Materials Science & Technology,27(4),317-324.
MLA	X. Han,et al."In vitro Biological Effects of Ti2448 Alloy Modified by Micro-arc Oxidation and Alkali Heatment".Journal of Materials Science & Technology 27.4(2011):317-324.