Synthesis and characterization of organometallic rhenium(I) and technetium(I) bile acid complexes

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2004-2010年

	Synthesis and characterization of organometallic rhenium(I) and technetium(I) bile acid complexes
	Huang, LL ; Zhu, H ; Xu, XP ; Zhang, CC ; Shen, YM
刊名	JOURNAL OF ORGANOMETALLIC CHEMISTRY
	2009
卷号	694 期号:20 页码:7
关键词	Tricarbonyl rhenium Tricarbonyl technetium Bile acids
ISSN号	0022-328X
通讯作者	Shen, YM (reprint author), Chinese Acad Sci, Res Ctr Radiopharmaceut, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
英文摘要	Eight bile acid derivatives have been synthesized with alkyl chains of various length based tridentate ligand chelating system. These derivatives have been reacted with the precursor [Et(4)N](2)[Re(CO)(3)Br(3)] and fac-[M(CO)(3) (H(2)O)(3)](+) (M = (99m)Tc, Re) in ethanol or ethanol-aqueous media to form water-soluble and stable organometallic complexes in good yields. (1)H NMR, (13)C NMR, IR and elemental analysis or HRMS spectroscopic analyses confirmed the tridentate complexation of the metal - tricarbonyl fragment exclusively via the tridentate chelates. In addition, the corresponding radioactive technetium-99m complexes were prepared successfully and challenged for stability in physiological phosphate buffer at 37 degrees C for 24 h. No decomposition of the complexes could be detected under the condition proving the stability of these complexes. (C) 2009 Elsevier B.V. All rights reserved.
学科主题	Chemistry
收录类别	SCI
语种	英语
WOS记录号	WOS:000268988500005
公开日期	2012-04-11
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/7073]
专题	上海应用物理研究所_中科院上海应用物理研究所2004-2010年
推荐引用方式 GB/T 7714	Huang, LL,Zhu, H,Xu, XP,et al. Synthesis and characterization of organometallic rhenium(I) and technetium(I) bile acid complexes[J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY,2009,694(20):7.
APA	Huang, LL,Zhu, H,Xu, XP,Zhang, CC,&Shen, YM.(2009).Synthesis and characterization of organometallic rhenium(I) and technetium(I) bile acid complexes.JOURNAL OF ORGANOMETALLIC CHEMISTRY,694(20),7.
MLA	Huang, LL,et al."Synthesis and characterization of organometallic rhenium(I) and technetium(I) bile acid complexes".JOURNAL OF ORGANOMETALLIC CHEMISTRY 694.20(2009):7.