Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.
	Wang, Peng-Cheng 1,3; Ran, Xin-Hui 1; Chen, Rui 1; Luo, Huai-Rong1 ; Ma, Qing-Yun 2; Liu, Yu-Qing 1; Hu, Jiang-Miao1 ; Huang, Sheng-Zhuo 1; Jiang, He-Zhong 1; Chen, Zhong-Quan 1
刊名	CHEMISTRY & BIODIVERSITY
	2011-10-01
卷号	8 期号:10 页码:1908-1913
关键词	NERVE GROWTH-FACTOR RAT IDENTIFICATION CONSTITUENTS RECEPTORS JATAMANSI CELLS
ISSN号	1612-1872
通讯作者	Zhou, J (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
英文摘要	Two new guaiane-type sesquiterpenoids, valerol A (1) and kessyl 3-acetate (2), together with nine known compounds, valeracetate (3), anismol A (4), orientalol C (5), spatulenol (6), 4 alpha, 10 alpha-epoxyaromadendrane (7), (+)-8-hydroxypinoresinol (8), pinorespiol (9), pinoresinol 4-O-beta-D-glucopyranoside (10), and 8-hydroxypinoresinol 4'-O-beta-D-glucopyranoside (11) were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1 and 2 were elucidated on the basis of spectroscopic methods (1D- and 2D-NMR, MS, UV, and IR). These compounds were evaluated for inhibitory activity on acetylcholinesterase (AChE) and enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells.
学科主题	Biochemistry & Molecular Biology; Chemistry
类目[WOS]	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]	NERVE GROWTH-FACTOR ; RAT ; IDENTIFICATION ; CONSTITUENTS ; RECEPTORS ; JATAMANSI ; CELLS
收录类别	SCI
资助信息	State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany[P2008-ZZ22]; Department of Science and Technology in Yunnan Province[20080A007]; Natural Science Foundation of Yunnan[2008CD159]
语种	英语
WOS记录号	WOS:000296503800010
公开日期	2012-04-10
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/5413]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Wang, Peng-Cheng,Ran, Xin-Hui,Chen, Rui,et al. Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.[J]. CHEMISTRY & BIODIVERSITY,2011,8(10):1908-1913.
APA	Wang, Peng-Cheng.,Ran, Xin-Hui.,Chen, Rui.,Luo, Huai-Rong.,Ma, Qing-Yun.,...&Zhao, You-Xing.(2011).Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L..CHEMISTRY & BIODIVERSITY,8(10),1908-1913.
MLA	Wang, Peng-Cheng,et al."Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.".CHEMISTRY & BIODIVERSITY 8.10(2011):1908-1913.