Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities
	Zhu, WM ; He, HP ; Fan, LM ; Shen, YM ; Zhou, J; Hao, XJ
刊名	JOURNAL OF INTEGRATIVE PLANT BIOLOGY
	2005-07-01
卷号	47 期号:7 页码:892-896
关键词	alkaloid Apocynaceae bronchodilatation Winchia calophylla
英文摘要	The Dai medicinal plant Winchia calophylla A. DC. (Apocynaceae) has efficacy as an anti-cough and anti-asthmatic medication. In order to investigate its relative bioactive components, we studied the chemical constituents of this plant. Using repeated column chromatography, 28 compounds, including loganin, six phenolic compounds, 17 indole alkaloids, three pyridine alkaloids, and a quinoline alkaloid, were isolated from the stem barks of W. calophylla. Loganin, paeonol, N (4)-methyl akuammicine, and cantleyine exhibited a moderate relaxation effect on isolated smooth muscles of guinea-pig tracheal spirals and lung strips and may be the bioactive components responsible for the bronchodilation produced by W. calophylla.
学科主题	Biochemistry & Molecular Biology; Plant Sciences
类目[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]	ALSTONIA-SCHOLARIS ; EVODIA-RUTAECARPA ; ALKALOIDS ; LEAVES ; CONSTITUENTS ; PHILIPPINES ; RUTACEAE
收录类别	SCI
语种	英语
WOS记录号	WOS:000230290500014
公开日期	2012-04-05
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/5148]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Peoples R China 2.Ocean Univ China, Marine Drug & Food Inst, Key Lab Marine Drugs Shandong Prov, Minist Educ, Qingdao 266003, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Zhu, WM,He, HP,Fan, LM,et al. Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2005,47(7):892-896.
APA	Zhu, WM,He, HP,Fan, LM,Shen, YM,Zhou, J,&Hao, XJ.(2005).Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,47(7),892-896.
MLA	Zhu, WM,et al."Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 47.7(2005):892-896.