A gold nanoparticle-based strategy for label-free and colorimetric screening of DNA triplex binders

	A gold nanoparticle-based strategy for label-free and colorimetric screening of DNA triplex binders
	Chen CE ; Song GT ; Yang XJ ; Ren JS ; Qu XG
刊名	biochimie
	2010
卷号	92 期号:10 页码:1416-1421
关键词	C-MYC GENE FORMING OLIGONUCLEOTIDES STRUCTURAL SELECTIVITY HELICAL DNA BINDING ANTIGENE CELLS STABILIZATION INTERCALATORS INHIBITION
ISSN号	0300-9084
通讯作者	ren js
中文摘要	a label-free colorimetric assay, using non-crosslinking aunp aggregation, has been developed for the screening of specific triplex dna binders. the relative binding affinities can be simultaneously determined. our novel assay is simple in design and fast in operation, avoiding either aunps modification or oligonucleotide labeling, and easy to implement for visual detection. this strategy may offer a new approach for developing low cost, sensitive and high-throughput screening platform that is likely to be highly useful in a wide range of applications. (c) 2010 elsevier masson sas. all rights reserved.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000283637800019
公开日期	2012-04-25
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/43306]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Chen CE,Song GT,Yang XJ,et al. A gold nanoparticle-based strategy for label-free and colorimetric screening of DNA triplex binders[J]. biochimie,2010,92(10):1416-1421.
APA	Chen CE,Song GT,Yang XJ,Ren JS,&Qu XG.(2010).A gold nanoparticle-based strategy for label-free and colorimetric screening of DNA triplex binders.biochimie,92(10),1416-1421.
MLA	Chen CE,et al."A gold nanoparticle-based strategy for label-free and colorimetric screening of DNA triplex binders".biochimie 92.10(2010):1416-1421.