Luminescent Porous Silica Fibers as Drug Carriers

	Luminescent Porous Silica Fibers as Drug Carriers
	Hou ZY ; Zhang CM ; Li CX ; Xu ZH ; Cheng ZY ; Li GG ; Wang WX ; Peng C ; Lin J
刊名	chemistry-a european journal
	2010
卷号	16 期号:48 页码:14513-14519
关键词	CARBOXYLIC-ACID SOLVOLYSIS ORDERED MESOPOROUS SILICA WHITE-LIGHT EMISSION CONTROLLED-RELEASE CARBON NANOTUBES DELIVERY SYSTEM MODIFIED MCM-41 FACILE METHOD PORE-SIZE IN-VITRO
ISSN号	0947-6539
通讯作者	hou zy
中文摘要	luminescent and porous silica fibers have been successfully prepared by using the electrospinning process. the obtained multifunctional silica fibers, which possess a porous structure and display blue luminescence, can serve as a drug delivery host carrier, using ibuprofen (ibu) as a model drug, allowing the investigation of storage/release properties. scanning electron microscopy (sem), transmission electron microscopy (tem), fourier-transform infrared spectroscopy (ft-ir), n-2 adsorption/desorption, photoluminescence (pl) spectra, and kinetic decay were used to characterize the structural, morphological, and optical properties of the as-obtained samples. the results reveal that the multifunctional silica materials exhibit an irregular porous structure, and display a fiberlike morphology with dimensions of several hundred nanometers in width and several millimeters in length. the obtained silica fibers exhibit an intense broad bluish emission, which might be attributed to impurities and/or defects in the silica fibers. the ibu-loaded silica fiber system shows blue luminescence under uv irradiation and controlled release behavior for ibu. in addition, the emission intensities of silica fibers in the drug carrier system vary with the released amount of ibu, thus allowing the drug release to be easily tracked and monitored by the change of the luminescence intensity.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000286484800040
公开日期	2012-04-25
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/43219]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Hou ZY,Zhang CM,Li CX,et al. Luminescent Porous Silica Fibers as Drug Carriers[J]. chemistry-a european journal,2010,16(48):14513-14519.
APA	Hou ZY.,Zhang CM.,Li CX.,Xu ZH.,Cheng ZY.,...&Lin J.(2010).Luminescent Porous Silica Fibers as Drug Carriers.chemistry-a european journal,16(48),14513-14519.
MLA	Hou ZY,et al."Luminescent Porous Silica Fibers as Drug Carriers".chemistry-a european journal 16.48(2010):14513-14519.