A small internal antisense RNA (aftsH) of all3642 (ftsH) in Anabaena sp PCC 7120

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	A small internal antisense RNA (aftsH) of all3642 (ftsH) in Anabaena sp PCC 7120
	Gong YangMin; Xu XuDong
刊名	CHINESE SCIENCE BULLETIN
	2012-03-01
卷号	57 期号:7 页码:756-761
关键词	antisense RNA Anabaena 7120 ftsH genes
ISSN号	1001-6538
通讯作者	Xu, XD (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
中文摘要	In bacteria, FtsH proteases are involved in quality maintenance of membrane proteins and cellular regulation at the level of protein stability. Among the 4 predicted ftsH genes in the cyanobacterium Anabaena sp. PCC 7120, namely alr1262, all3642, all4776 and all4936, at least the first two showed reduced transcription in specialized N-2-fixing cells called heterocysts. In contrast, the transcription of a small internal antisense RNA (aftsH) of all3642 was up-regulated in heterocysts. Overexpression of the antisense RNA suppressed the expression of all3642, alr1262 and all4776. Control of promoter and modulation by antisense RNA may both contribute to gene regulation in heterocysts of filamentous cyanobacteria.
英文摘要	In bacteria, FtsH proteases are involved in quality maintenance of membrane proteins and cellular regulation at the level of protein stability. Among the 4 predicted ftsH genes in the cyanobacterium Anabaena sp. PCC 7120, namely alr1262, all3642, all4776 and all4936, at least the first two showed reduced transcription in specialized N-2-fixing cells called heterocysts. In contrast, the transcription of a small internal antisense RNA (aftsH) of all3642 was up-regulated in heterocysts. Overexpression of the antisense RNA suppressed the expression of all3642, alr1262 and all4776. Control of promoter and modulation by antisense RNA may both contribute to gene regulation in heterocysts of filamentous cyanobacteria.
WOS标题词	Science & Technology
类目[WOS]	Multidisciplinary Sciences
研究领域[WOS]	Science & Technology - Other Topics
关键词[WOS]	SYNECHOCYSTIS SP PCC-6803 ; SP-STRAIN PCC-7120 ; CYANOBACTERIUM ANABAENA ; PROTEASE ; GENE ; EXPRESSION ; MEMBRANE ; PATTERN
收录类别	SCI
资助信息	National Natural Science Foundation of China[30825003, 30770049]
语种	英语
WOS记录号	WOS:000300771200009
公开日期	2012-04-01
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/342005/16769]
专题	水生生物研究所_藻类生物学及应用研究中心_期刊论文
作者单位	Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
推荐引用方式 GB/T 7714	Gong YangMin,Xu XuDong. A small internal antisense RNA (aftsH) of all3642 (ftsH) in Anabaena sp PCC 7120[J]. CHINESE SCIENCE BULLETIN,2012,57(7):756-761.
APA	Gong YangMin,&Xu XuDong.(2012).A small internal antisense RNA (aftsH) of all3642 (ftsH) in Anabaena sp PCC 7120.CHINESE SCIENCE BULLETIN,57(7),756-761.
MLA	Gong YangMin,et al."A small internal antisense RNA (aftsH) of all3642 (ftsH) in Anabaena sp PCC 7120".CHINESE SCIENCE BULLETIN 57.7(2012):756-761.