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	Different setup errors assessed by weekly cone-beam computed tomography on different registration in nasopharyngeal carcinoma treated with intensity-modulated radiation therapy
	Su, Jiqing; Chen, Wen; Yang, Huiyun; Hong, Jidong; Zhang, Zijian; Yang, Guangzheng; Li, Li; Wei, Rui*
刊名	OncoTargets and Therapy
	2015
卷号	8页码:2545-2553
关键词	The study aimed to investigate the difference of setup errors on different registration in the treatment of nasopharyngeal carcinoma based on weekly cone-beam computed tomography (CBCT). Thirty nasopharyngeal cancer patients scheduled to undergo intensity-modulated radiotherapy (IMRT) were prospectively enrolled in the study. Each patient had a weekly CBCT before radiation therapy. In the entire study 201 CBCT scans were obtained. The scans were registered to the planning CT to determine the difference of setup errors on different registration sites. Different registration sites were represented by bony landmarks. Nasal septum and pterygoid process represent head cervical vertebrae 1–3 represent upper neck and cervical vertebrae 4–6 represent lower neck. Patient positioning errors were recorded in the right–left (RL) superior–inferior (SI) and anterior–posterior (AP) directions over the course of radiotherapy. Planning target volume margins were calculated from the systematic and random errors. In this study we can make a conclusion that there are setup errors in RL SI and AP directions of nasopharyngeal carcinoma patients undergoing IMRT. In addition the head and neck setup error has the difference with statistical significance while patient setup error of neck is greater than that of head during the course of radiotherapy. In our institution we recommend a planning target volume margin of 3.0 mm in RL direction 1.3 mm in SI direction and 2.6 mm in AP direction for nasopharyngeal cancer patients undergoing IMRT with weekly CBCT scans.
ISSN号	1178-6930
DOI	10.2147/OTT.S87159
URL标识	查看原文
WOS记录号	WOS:000361125500001
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/3342002
专题	中南大学
作者单位	[Su, Jiqing] Changsha Cent Hosp, Dept Oncol, Changsha, Hunan, Peoples R China.
推荐引用方式 GB/T 7714	Su, Jiqing,Chen, Wen,Yang, Huiyun,et al. Different setup errors assessed by weekly cone-beam computed tomography on different registration in nasopharyngeal carcinoma treated with intensity-modulated radiation therapy[J]. OncoTargets and Therapy,2015,8:2545-2553.
APA	Su, Jiqing.,Chen, Wen.,Yang, Huiyun.,Hong, Jidong.,Zhang, Zijian.,...&Wei, Rui*.(2015).Different setup errors assessed by weekly cone-beam computed tomography on different registration in nasopharyngeal carcinoma treated with intensity-modulated radiation therapy.OncoTargets and Therapy,8,2545-2553.
MLA	Su, Jiqing,et al."Different setup errors assessed by weekly cone-beam computed tomography on different registration in nasopharyngeal carcinoma treated with intensity-modulated radiation therapy".OncoTargets and Therapy 8(2015):2545-2553.

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