Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)

	Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)
	Kurskaya, Olga; Ryabichenko, Tatyana; Leonova, Natalya; Shi, Weifeng; Bi, Hongtao; Sharshov, Kirill; Kazachkova, Eugenia; Sobolev, Ivan; Prokopyeva, Elena; Kartseva, Tatiana
刊名	PLOS ONE
	2018
卷号	13 期号:9
英文摘要	Background Acute respiratory infections (ARIs) cause a considerable morbidity and mortality worldwide especially in children. However, there are few studies of the etiological structure of ARIs in Russia. In this work, we analyzed the etiology of ARIs in children (0-15 years old) admitted to Novosibirsk Children's Municipal Clinical Hospital in 2013-2017. Methods We tested nasal and throat swabs of 1560 children with upper or lower respiratory infection for main respiratory viruses (influenza viruses A and B, parainfluenza virus types 1-4, respiratory syncytial virus, metapneumovirus, four human coronaviruses, rhinovirus, adenovirus and bocavirus) using a RT-PCR Kit. Results We detected 1128 (72.3%) samples were positive for at least one virus. The most frequently detected pathogens were respiratory syncytial virus (358/1560, 23.0%), influenza virus (344/1560, 22.1%), and rhinovirus (235/1560, 15.1%). Viral co-infections were found in 163 out of the 1128 (14.5%) positive samples. We detected significant decrease of the respiratory syncytial virus-infection incidence in children with increasing age, while the reverse relationship was observed for influenza viruses. Conclusions We evaluated the distribution of respiratory viruses in children with ARIs and showed the prevalence of respiratory syncytial virus and influenza virus in the etiological structure of infections. This study is important for the improvement and optimization of diagnostic tactics, control and prevention of the respiratory viral infections.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/59967]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Kurskaya, Olga,Ryabichenko, Tatyana,Leonova, Natalya,et al. Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)[J]. PLOS ONE,2018,13(9).
APA	Kurskaya, Olga.,Ryabichenko, Tatyana.,Leonova, Natalya.,Shi, Weifeng.,Bi, Hongtao.,...&Shestopalov, Alexander.(2018).Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017).PLOS ONE,13(9).
MLA	Kurskaya, Olga,et al."Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)".PLOS ONE 13.9(2018).