Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro [isobenzofuran-1,3 '-isochroman] scaffolds

doi:10.1039/c6ob02802k

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	Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro [isobenzofuran-1,3 '-isochroman] scaffolds
	Tao, Hua 3; Liang, Jianping1 ; Xin, Zhijun1 ; Jiang, Tingting 1,2; Du, Wenyue 1; Lu, Xihong1 ; Zhou, Xiang 1; Li, Xuehu1 ; Wang, Liang 1,2
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2017-03-21
卷号	15 页码:2403-2410
ISSN号	1477-0520
DOI	10.1039/c6ob02802k
英文摘要	A highly regioselective synthesis of functionalized 3H-spiro[isobenzofuran-1,3'-isochroman] scaffolds using a novel palladium-catalyzed tandem cyclization reaction is explored. During the reaction process, C-O, C-C and C-O bonds are sequentially formed in one pot via decarboxylative allenylpalladium formation, nucleophilic attack, arylpalladium addition and intramolecular nucleophilic attack.
资助项目	International S&T Cooperation Program of China[1504WKCA098] ; Gansu Province Special Funds for Gansu Medicine Industry Development[Y361010SJ0]
WOS关键词	CARBON TRIPLE BOND ; PROPARGYL CARBONATE ; DOMINO CYCLIZATION ; EFFICIENT ; HETEROCYCLES ; NITROGEN ; BROMIDES ; ALKYNES
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000397945900014
资助机构	International S&T Cooperation Program of China ; Gansu Province Special Funds for Gansu Medicine Industry Development
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/44523]
专题	近代物理研究所_重离子辐照药物研发中心
通讯作者	Liang, Jianping; Xin, Zhijun
作者单位	1.Chinese Acad Sci, Inst Modern Phys, 509 Nanchang Rd, Lanzhou 730000, Gansu, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Northwest Inst Ecoenvironm & Resources, 320 Western Dong Gang Rd, Lanzhou 730000, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Tao, Hua,Liang, Jianping,Xin, Zhijun,et al. Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro [isobenzofuran-1,3 '-isochroman] scaffolds[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2017,15:2403-2410.
APA	Tao, Hua.,Liang, Jianping.,Xin, Zhijun.,Jiang, Tingting.,Du, Wenyue.,...&Wang, Liang.(2017).Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro [isobenzofuran-1,3 '-isochroman] scaffolds.ORGANIC & BIOMOLECULAR CHEMISTRY,15,2403-2410.
MLA	Tao, Hua,et al."Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro [isobenzofuran-1,3 '-isochroman] scaffolds".ORGANIC & BIOMOLECULAR CHEMISTRY 15(2017):2403-2410.