Dependence of Relative Biological Effectiveness on Dose in Hypofractionated Carbon Ion Beam Radiotherapy

CORC > 近代物理研究所 > 中国科学院近代物理研究所 > 兰州重离子研究装置

	Dependence of Relative Biological Effectiveness on Dose in Hypofractionated Carbon Ion Beam Radiotherapy
	Dai Zhongying; Chen Weiqiang; Li Qiang; Dai Tianyuan; Liu Xinguo
刊名	Nuclear Physics Review
	2017
卷号	34 页码:784-789
ISSN号	1007-4627
英文摘要	Short treatment course due to the suitability of hypofractionated regimen for carbon ion beam is one of the advantages of carbon ion radiotherapy. To study the dependence of relative biological effectiveness (RBE) on dose,the relationship between RBE and dose was deduced through the linear-quadratic (LQ) model. Based on the relationship,the change of RBE of tumor cells and normal tissue cells with different radiosensitivities with dose was studied. The results showed that the RBE value of tumor cells was always greater than that of normal tissue cells in the dose range of 0~20 Gy,regardless of the radiosensitivity of tumor and normal tissue cells. In addition,based on theoretical deduction and analysis of the relevant experimental data,the existence of RBE increase with increasing dose was verified. These results are of great significance for conducting hypofractionated radiotherapy with carbon ion beam.
CSCD记录号	CSCD:6165494
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/59889]
专题	近代物理研究所_兰州重离子研究装置近代物理研究所_生物物理研究室
推荐引用方式 GB/T 7714	Dai Zhongying,Chen Weiqiang,Li Qiang,et al. Dependence of Relative Biological Effectiveness on Dose in Hypofractionated Carbon Ion Beam Radiotherapy[J]. Nuclear Physics Review,2017,34:784-789.
APA	Dai Zhongying,Chen Weiqiang,Li Qiang,Dai Tianyuan,&Liu Xinguo.(2017).Dependence of Relative Biological Effectiveness on Dose in Hypofractionated Carbon Ion Beam Radiotherapy.Nuclear Physics Review,34,784-789.
MLA	Dai Zhongying,et al."Dependence of Relative Biological Effectiveness on Dose in Hypofractionated Carbon Ion Beam Radiotherapy".Nuclear Physics Review 34(2017):784-789.