Visualizing the changes in the cellular redox environment using a novel profluorescent rhodamine nitroxide probe

doi:10.1039/c3nj00674c

	Visualizing the changes in the cellular redox environment using a novel profluorescent rhodamine nitroxide probe
	Guo, Y (reprint author), Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China.; Guo, Y 2; Shao, SJ 2; Li, Q2 ; Cao, LY 2; Wu, QF 2
刊名	NEW JOURNAL OF CHEMISTRY
	2013
卷号	37 页码:2991-2994
关键词	Perylenebisimide-linked Nitroxide Oxidative Stress Ascorbic-acid Living Cells Fluorescent-probes Hydroxyl Radicals Cancer-cells Spin Labels Rat-liver Reduction
ISSN号	1144-0546
DOI	10.1039/c3nj00674c
英文摘要	A novel rhodamine nitroxide probe was synthesized for monitoring the cellular redox environment based on the reduction of the nitroxide to hydroxylamine. It displayed selective and sensitive response to biological reducing compounds. The different effects of anticancer agent 2-deoxyglucose on the redox environment of normal human liver cells and human hepatoma cells were studied by fluorescence imaging.
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WOS关键词	PERYLENEBISIMIDE-LINKED NITROXIDE ; OXIDATIVE STRESS ; ASCORBIC-ACID ; LIVING CELLS ; FLUORESCENT-PROBES ; HYDROXYL RADICALS ; CANCER-CELLS ; SPIN LABELS ; RAT-LIVER ; REDUCTION
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000324758700008
资助机构	National Basic Research Program of China (973 Program) [2010CB834203] ; National Basic Research Program of China (973 Program) [2010CB834203] ; National Natural Science Foundation of China [U1232207, 11075191] ; National Natural Science Foundation of China [U1232207, 11075191] ; Chinese Academy of Sciences [Y162100XB0, Y1621130SJ0] ; Chinese Academy of Sciences [Y162100XB0, Y1621130SJ0] ; Gansu Provincial Funds for Distinguished Young Scholar [1111RJDA010] ; Gansu Provincial Funds for Distinguished Young Scholar [1111RJDA010]
内容类型	期刊论文
源URL	[http://ir.impcas.ac.cn/handle/113462/18583]
专题	近代物理研究所_医学物理研究室近代物理研究所_生物物理研究室
通讯作者	Guo, Y (reprint author), Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China.
作者单位	1.Xiao, Guoqing] Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China 2.[Li, Qiang 3.Liu, Xinguo 4.Dai, Zhongying 5.Shen, Guosheng 6.He, Pengbo 7.Huang, Qiyan 8.Yan, Yuanlin 9.Jin, Xiaodong 10.Ye, Fei
推荐引用方式 GB/T 7714	Guo, Y ,Guo, Y,Shao, SJ,et al. Visualizing the changes in the cellular redox environment using a novel profluorescent rhodamine nitroxide probe[J]. NEW JOURNAL OF CHEMISTRY,2013,37:2991-2994.
APA	Guo, Y ,Guo, Y,Shao, SJ,Li, Q,Cao, LY,&Wu, QF.(2013).Visualizing the changes in the cellular redox environment using a novel profluorescent rhodamine nitroxide probe.NEW JOURNAL OF CHEMISTRY,37,2991-2994.
MLA	Guo, Y ,et al."Visualizing the changes in the cellular redox environment using a novel profluorescent rhodamine nitroxide probe".NEW JOURNAL OF CHEMISTRY 37(2013):2991-2994.