Heavy-ion conformal irradiation in the shallow-seated tumor therapy terminal at HIRFL

doi:10.1007/s11517-007-0245-3

CORC > 近代物理研究所 > 中国科学院近代物理研究所 > 近代物理研究所知识存储（2010之前）

	Heavy-ion conformal irradiation in the shallow-seated tumor therapy terminal at HIRFL
	Li, Qiang; Dai, Zhongying; Yan, Zheng; Jin, Xiaodong; Liu, Xinguo; Xiao, Guoqing
刊名	MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
	2007-11-01
卷号	45 期号:11 页码:1037-1043
关键词	heavy-ion cancer therapy conformal irradiation beam delivery system irradiation field range modulator
ISSN号	0140-0118
DOI	10.1007/s11517-007-0245-3
英文摘要	Basic research related to heavy-ion cancer therapy has been done at the Institute of Modern Physics (IMP), Chinese Academy of Sciences since 1995. Now a plan of clinical trial with heavy ions has been launched at IMP. First, superficially placed tumor treatment with heavy ions is expected in the therapy terminal at the Heavy Ion Research Facility in Lanzhou (HIRFL), where carbon ion beams with energy up to 100 MeV/u can be supplied. The shallow-seated tumor therapy terminal at HIRFL is equipped with a passive beam delivery system including two orthogonal dipole magnets, which continuously scan pencil beams laterally and generate a broad and uniform irradiation field, a motor-driven energy degrader and a multi-leaf collimator. Two different types of range modulator, ripple filter and ridge filter with which Guassian-shaped physical dose and uniform biological effective dose Bragg peaks can be shaped for therapeutic ion beams respectively, have been designed and manufactured. Therefore, two-dimensional and three-dimensional conformal irradiations to tumors can be performed with the passive beam delivery system at the earlier therapy terminal. Both the conformal irradiation methods have been verified experimentally and carbon-ion conformal irradiations to patients with superficially placed tumors have been carried out at HIRFL since November 2006.
WOS关键词	BEAM 3-DIMENSIONAL IRRADIATION ; DEPTH-DOSE DISTRIBUTION ; SYSTEM ; RADIOTHERAPY ; LANZHOU ; DESIGN ; PROTON ; PROJECT ; FILTER ; HIMAC
WOS研究方向	Computer Science ; Engineering ; Mathematical & Computational Biology ; Medical Informatics
语种	英语
出版者	SPRINGER HEIDELBERG
WOS记录号	WOS:000251097800006
公开日期	2010-10-29
内容类型	期刊论文
源URL	[http://ir.imp.cas.cn/handle/113462/5853]
专题	近代物理研究所_近代物理研究所知识存储（2010之前）近代物理研究所_兰州重离子研究装置
通讯作者	Li, Qiang
作者单位	Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Li, Qiang,Dai, Zhongying,Yan, Zheng,et al. Heavy-ion conformal irradiation in the shallow-seated tumor therapy terminal at HIRFL[J]. MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING,2007,45(11):1037-1043.
APA	Li, Qiang,Dai, Zhongying,Yan, Zheng,Jin, Xiaodong,Liu, Xinguo,&Xiao, Guoqing.(2007).Heavy-ion conformal irradiation in the shallow-seated tumor therapy terminal at HIRFL.MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING,45(11),1037-1043.
MLA	Li, Qiang,et al."Heavy-ion conformal irradiation in the shallow-seated tumor therapy terminal at HIRFL".MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING 45.11(2007):1037-1043.