Treatment planning for scanned ion beams

	Treatment planning for scanned ion beams
	Haberer, T ; Kramer, M ; Jakel, O ; Rietzel, E ; Schardt, D ; Scholz, M ; Wang, JF ; Weber, U ; Weyrather, W
	2004-12
关键词	scanned ion beams treatment planning radiotherapy
卷号	73
页码	S80-S85
英文摘要	Since 1997 a radiotherapy unit using fast carbon ions is operational at GSI. An intensity-controlled magnetic raster scanner together with a synchrotron allowing fast energy variation enable a unique method of purely active dose shaping in three dimensions. This contribution describes the necessary steps to establish a treatment planning system for this novel modality. We discuss the requirements for the physical beam model and the radiobiological model. Based on these we chose to implement a home-grown pencil beam model to describe the ion-tissue interaction and the Local Effect Model to calculate the RBE voxel-by-voxel. Given the large number of degrees of freedom biological dose optimization must be achieved by means of inverse treatment planning. All ion-related aspects are collected in our TRiP98 software. Biological dosimetry measuring cell survival in two dimensions turns out to be a good way to verify the model predictions as well as the actual irradiation procedure. We show a patient example and outline the future steps towards a dedicated clinic facility for all light ions.
会议录	RADIOTHERAPY AND ONCOLOGY
会议录出版者	ELSEVIER SCI IRELAND LTD
会议录出版地	CUSTOMER RELATIONS MANAGER, BAY 15, SHANNON INDUSTRIAL ESTATE CO, CLARE, IRELAND
语种	英语
WOS研究方向	Oncology ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000227647500021
内容类型	会议论文
源URL	[http://119.78.100.186/handle/113462/58283]
专题	中国科学院近代物理研究所
通讯作者	Kramer, M
作者单位	1.GSI Biophys, D-64291 Darmstadt, Germany 2.DKFZ, D-69120 Heidelberg, Germany 3.IMP, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Haberer, T,Kramer, M,Jakel, O,et al. Treatment planning for scanned ion beams[C]. 见:.