The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines

doi:10.2478/raon-2013-0045

	The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines
	Zhao, Jin 1; Guo, Zhong 1; Zhang, Hong2 ; Wang, Zhenhua 3; Song, Lei 1; Ma, Jianxiu 1; Pei, Shuyan 1; Wang, Chenjing 1
刊名	RADIOLOGY AND ONCOLOGY
	2013-09-01
卷号	47 页码:247-257
关键词	Human Tumour Cells Carbon Ions X-rays Radiation Sensitivity Dna Double Strand Breaks Gamma H2ax
ISSN号	1318-2099
DOI	10.2478/raon-2013-0045
文献子类	Article
英文摘要	Background. Carbon ions (C-12(6+)) are high linear energy transfer (LET) radiation characterized by higher relative biological effectiveness than low LET radiation. The assessment of tumour radiosensitivity would be particularly useful in optimizing the radiation dose during radiotherapy. The aim of the current study was to evaluate the potential value of the neutral comet assay and gamma H2AX foci assay in assessing C-12(6+) radiosensitivity of tumour cells.
资助项目	Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry[[2011]1568]
WOS关键词	DOUBLE-STRAND BREAKS ; CLUSTERED DNA LESIONS ; HIGH-LET ; HUMAN FIBROBLASTS ; MAMMALIAN-CELLS ; RADIATION ; DAMAGE ; REPAIR ; IRRADIATION ; IONS
WOS研究方向	Oncology ; Radiology, Nuclear Medicine & Medical Imaging
语种	英语
出版者	ASSOC RADIOLOGY & ONCOLOGY
WOS记录号	WOS:000322968000008
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/48181]
专题	中国科学院近代物理研究所
通讯作者	Zhao, Jin
作者单位	1.Northwest Univ Nationalities, Coll Med, Lanzhou 730030, Peoples R China 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China 3.Yantai Univ, Sch Life Sci, Yantai 264005, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Jin,Guo, Zhong,Zhang, Hong,et al. The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines[J]. RADIOLOGY AND ONCOLOGY,2013,47:247-257.
APA	Zhao, Jin.,Guo, Zhong.,Zhang, Hong.,Wang, Zhenhua.,Song, Lei.,...&Wang, Chenjing.(2013).The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines.RADIOLOGY AND ONCOLOGY,47,247-257.
MLA	Zhao, Jin,et al."The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines".RADIOLOGY AND ONCOLOGY 47(2013):247-257.