The mean first passage time and stochastic resonance in gene transcriptional system with time delay | |
Feng, Y. L.1; Zhu, J.1; Zhang, M.1; Gao, L. L.1; Liu, Y. F.1; Dong, J. M.2 | |
刊名 | INTERNATIONAL JOURNAL OF MODERN PHYSICS B
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2016-04-30 | |
卷号 | 30页码:11 |
关键词 | Gene transcription time delay mean first passage time stochastic resonance |
ISSN号 | 0217-9792 |
DOI | 10.1142/S0217979216500673 |
英文摘要 | In this paper, the gene transcriptional dynamics driven by correlated noises are investigated, where the time delay for the synthesis of transcriptional factor is introduced. The effects of the noise correlation strength and time delay on the stationary probability distribution (SPD), the mean first passage time and the stochastic resonance (SR) are analyzed in detail based on the delay Fokker-Planck equation. It is found that both the time delay and noise correlation strength play important roles in the bistable transcriptional system. The effect of the correlation strength reduces but the time delay enhances the mean first passage time (MFPT). Finally, the SR for this gene transcriptional system is found to be enhanced by the time delay. |
WOS关键词 | BISTABLE KINETIC-MODEL ; DIFFERENTIAL EQUATIONS ; CORRELATED NOISES ; REGULATORY SYSTEM ; 1ST-PASSAGE TIME ; SIMULATION ; FEEDBACK ; DRIVEN ; OSCILLATOR ; EXPRESSION |
WOS研究方向 | Physics |
语种 | 英语 |
出版者 | WORLD SCIENTIFIC PUBL CO PTE LTD |
WOS记录号 | WOS:000376088700006 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.186/handle/113462/42635] ![]() |
专题 | 中国科学院近代物理研究所 |
通讯作者 | Liu, Y. F. |
作者单位 | 1.Lanzhou Univ, Hosp 2, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China |
推荐引用方式 GB/T 7714 | Feng, Y. L.,Zhu, J.,Zhang, M.,et al. The mean first passage time and stochastic resonance in gene transcriptional system with time delay[J]. INTERNATIONAL JOURNAL OF MODERN PHYSICS B,2016,30:11. |
APA | Feng, Y. L.,Zhu, J.,Zhang, M.,Gao, L. L.,Liu, Y. F.,&Dong, J. M..(2016).The mean first passage time and stochastic resonance in gene transcriptional system with time delay.INTERNATIONAL JOURNAL OF MODERN PHYSICS B,30,11. |
MLA | Feng, Y. L.,et al."The mean first passage time and stochastic resonance in gene transcriptional system with time delay".INTERNATIONAL JOURNAL OF MODERN PHYSICS B 30(2016):11. |
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